ABOUT US

The Neural Computation Laboratory (NCL), led by Professors Beverley Clark and Dr Arnd Roth, is part of the Wolfson Institute for Biomedical Research at UCL. The group’s research focuses on understanding computations in neural circuits during behaviour. To this end, the group is combining experimental and theoretical approaches to examine computations in cortical and cerebellar circuits. Over the past decade we have been developing new strategies for probing the function of single neurons and networks of neurons in the intact mammalian brain. We have considerable experience in combining a wide range of techniques, from patch-clamp recordings, two-photon imaging, the use of transgenic mouse lines and genetically encoded calcium sensors, through to electron microscopy for tracing the wiring diagram of the underlying circuits.
Please note this post is not eligible for visa sponsorship due to the salary threshold criteria and a current right to work is therefore required.

This is an excellent opportunity for an applicant already experienced in mouse breeding and management of transgenic colonies to extend their skills in the research environment and contribute to cutting edge research in cellular and systems neuroscience. The postholder will manage 10 transgenic mouse lines and will be responsible, as part of a cross-lab team, for operational and practical aspects of running a multi-user serial 2-photon tomography facility (‘Rocksaw’, used for automated serial sectioning and imaging of whole brains). When trained, the postholder will act as trainer to other researchers to operate and troubleshoot ‘Rocksaw’ and will prepare and run samples for projects in the NCL. They will also help revise and oversee standard operating procedures for use of this facility. They will be responsible for preparing and maintaining standard operating procedures for animal work under the current Home Office Licence and will have opportunities to learn animal behavioural training and surgical procedures. They will assist in the day-to-day running of the laboratory; monitoring and maintaining stocks of lab consumables, preparing solutions, and providing support for experiments being carried out by research staff and PhD students. This role will include ensuring that health and safety policies are followed, and that the lab remains a clean and safe environment in which to work.