Scientist 2, Cell Culture, Protein Sciences at Genentech

Daly City, California, United States -

Full Time

Start Date

Immediate

Expiry Date

06 Feb, 26

Salary

155600.0

Posted On

08 Nov, 25

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Cell Culture, Protein Production, Mammalian Cell Culture, Transfection, Protein Expression, Troubleshooting, SDS-PAGE, Western-Blot Analysis, Flow Cytometry, Endotoxin Assays, Stable Cell Line Generation, BacMam, Protein Purification, Ultrafiltration, Organizational Skills, Multi-Tasking

Industry

Biotechnology Research

Description

The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech. The Opportunity The departments of BioMolecular Research and Structural Biology, within the Protein Sciences Organization at Genentech are looking for a versatile, dynamic, and independent individual to contribute towards medium to large scale mammalian recombinant protein expression. In this collaborative role, the successful candidate will have the opportunity to work with other scientists and group leaders within and outside our department, driving projects autonomously to fulfill both straightforward and challenging protein production needs. Job Responsibilities Design and execute cell culture strategies to efficiently express both routine and complex recombinant protein targets Carry out several aspects of mammalian cell culture including routine cell propagation, transfection, culture harvest at the 0.5 - 20L scale. Routinely evaluate, optimize, and implement new expression protocols and technologies to improve titer, yield, and quality. Proactively troubleshoot cell culture and expression challenges. Interact with informatics systems, document experimental procedures and data, and share results with team members Who You Are Applicants with a Bachelor’s degree in the Biological Sciences should have at least 3-4 years of scientific experience and applicants with a Master’s degree in the Biological Sciences should have at least 1 - 3 years of relevant experience Working expertise of mammalian cell culture (HEK293, CHO and others) for protein production at multiple-liter scale Practical experience in carrying out troubleshooting and optimizing protein expression Strong desire to learn new techniques, advance technologies related to protein production and interest in implementing new expression systems. Familiarity with protein analytical methods including SDS-PAGE, Western-blot analysis, flow cytometry, and endotoxin assays etc. Excellent organizational skills as well as the ability to multi-task and take responsibility Preferred Experience in stable cell line generation and BacMam is a plus Familiarity with protein purification and ultrafiltration would be highly desirable Relocation benefits are available for this posting. The expected salary range for this position based on the primary location of California is $83,800 to $155,600. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits #LI-KC2 Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Responsibilities

Design and execute cell culture strategies for recombinant protein expression. Optimize and troubleshoot cell culture and expression challenges while collaborating with team members.