DESCRIPTION

The HTE & Lead Discovery Capabilities group in Rahway is seeking a candidate to join their dynamic team whose mission is to invent and deploy enabling automated workflows to accelerate the discovery of new medicines. This lab-based role will involve the management of a variety of liquid handlers and automation platforms used for high-throughput synthetic experimentation. The successful candidate will work closely with project medicinal chemists to support them in the setup and execution of experiments.

REQUIRED SKILLS AND EXPERIENCE

• Basic familiarity with common laboratory instrumentation including, but not limited to, HPLC
• Basic familiarity with organic chemistry principles and nomenclature
• Daily use of Microsoft Word, Excel, PowerPoint
• Effective organizational, multi-tasking, and oral/written communications skills
• Minimum educational requirements include a BS or MS degree in chemistry or a closely related field including at least two semesters of organic chemistry

DESIRED SKILLS AND EXPERIENCE

• Experience with automated liquid handling platforms which may include, but are not limited to, Bravo, Tecan, Hamilton, Agilent, Thermo, TTP Labtech
• Experience in synthetic chemistry with a preference towards skills including high-throughput experimentation and purification
• Experience with analytical characterization of new entities, especially UPLC-MS
• Familiarity working with air sensitive chemistry techniques
• Familiarity with managing data sets and data visualization tools (Spotfire, etc.)

Qualifications - B.S./M.S. in Chemistry or a closely related field including at least two semesters of organic chemistry and relevant years of experience as listed below

• Scientist 1 - B.S. with 0-1 years of experience
• Scientist 2 - B.S. with 1-2 years of experience; M.S. with 0-1 years
• Scientist 3 - B.S. with 3-5 years of experience; M.S. with 1-2 year

ABOUT THIS ROLE

We are looking to fill a Scientist 1, 2, or 3 - Automation Chemist - Small Molecule position working as a full-time employee of Parexel FSP on long-term assignment onsite at one of our clients located in Rahway, NJ. This position offers full benefits, sick time, 401K, paid holidays, and paid time off. This role does not offer sponsorship.

RESPONSIBILITIES

• Maintain stocks of common lab consumables not regularly stocked by vendor (common solvents, plasticware etc.)
• Perform routine calibration, maintenance, and service coordination for a variety of lab equipment while implementing standard methods to evaluate the following: system performance (pipetting accuracy), chemistry performance (micro/nano), and solid phase extraction performance
• Under the direction and guidance of scientific supervisors, implement protocols assessing the performance of liquid handling platforms for chemical synthesis, reaction workup, and purification
• Standardize robotic labware and equipment across laboratory instruments
• Generate documentation and quick-start, end-to-end guides for newly developed automation protocols accessible to novice users
• Support new users on automation platforms and collaborate with experienced users to implement additional synthetic functionality
• Execute routine high-throughput synthetic experimentation including synthesis, workup, purification, data analysis, and report generation to support group innovation objectives
• Partner with laboratory safety officers to maintain and improve standard of safety within the lab

Qualifications - B.S./M.S. in Chemistry or a closely related field including at least two semesters of organic chemistry and relevant years of experience as listed below

• Scientist 1 - B.S. with 0-1 years of experience
• Scientist 2 - B.S. with 1-2 years of experience; M.S. with 0-1 years
• Scientist 3 - B.S. with 3-5 years of experience; M.S. with 1-2 years