Scientist I, in vitro & in vivo studies, I/O at ModeX Therapeutics

Weston, Massachusetts, United States -

Full Time

Start Date

Immediate

Expiry Date

18 Mar, 26

Salary

0.0

Posted On

18 Dec, 25

Experience

10 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Immunology, Immuno-Oncology, In Vitro Studies, In Vivo Studies, Biologic Drugs, Functional Assays, Flow Cytometry, ELISA, Luminex, Tumor Mouse Models, Data Analysis, Problem-Solving, Communication, Collaboration, Adaptability

Industry

Biotechnology Research

Description

ModeX Therapeutics is seeking a highly skilled and motivated Scientist I with experience in immuno-oncology/immunology to support the development and progression of new immune therapies. The successful candidate will work with ModeX’s team to test novel biologic drug candidates, delineate their mechanism of action, and address biological questions. This is an exciting opportunity to be part of a cross-functional team and contribute to the development of next-generation therapeutics in a fast-paced, rapidly growing biotech company with a bold vision. Key Responsibilities: * Play a key role in the development of new biologic drugs for immunotherapy * Independently propose, plan and perform in vitro and in vivo studies to characterize the company’s drug candidates and their mechanism of action * Establish mechanistic insights addressing the impact of novel targets on immune responses * Develop and perform complex functional assays using primary immune cells (human, mouse, NHP) * Design, develop, troubleshoot and establish in vitro assays and in vivo models and standard operating procedures as needed * Work collaboratively within the ModeX team Qualifications: * BS or MS in immunology, immuno-oncology, or related field * Lab experience required: BS with 10+ years or MS with 8+ years of research and professional experience * 5+ years of relevant industry experience required * Strong understanding of immunology, immunotherapy and immunoassay * Mastery of functional assays with primary immune cells, multi-color flow cytometry, ELISA and Luminex * Experience in handling mice incl. various dosing routes (IV, IP, SC), tumor mouse models and tissue collection * Excellent written and oral communication, organization, and data analysis skills * Outstanding troubleshooting and problem-solving skills * Highly adaptable to a fast-paced work environment and capable of working independently as well as within project teams ModeX Therapeutics is an Equal Opportunity Employer Qualifications ModeX Therapeutics, an OPKO Health company, is the leading clinical-stage biopharmaceutical company developing unique and proprietary-multispecific therapeutics. Its MSTAR platform unites the power of multiple biologics in a single molecule to create multispecific antibodies that bind four or more targets with unprecedented versatility and potency for complex diseases. Its promising first-in-class immunology pipeline includes candidates against immune diseases, including cancer (both solid and hematologic tumors), immune impairment, as well as several of the world's most pressing viral threats. Its founding team includes globally recognized medical innovators with proven track records of delivering breakthroughs for patients. ModeX is based in Weston, Massachusetts. For more information, please visit www.modextx.com.

Responsibilities

The successful candidate will play a key role in developing new biologic drugs for immunotherapy and will independently propose, plan, and perform in vitro and in vivo studies. They will also establish mechanistic insights and develop complex functional assays using primary immune cells.