We are seeking a Scientist II, Biomaterials, to join Aspect’s Preclinical Research & Development team. You will design, generate and characterize biomaterials that address specific bioprinted tissue therapeutic application needs while expanding the portfolio of biomaterials used in the production of these therapeutic implants for preclinical and nonclinical testing. Working closely with our team of scientists and engineers, you will play a pivotal role in the development of material strategy solutions for bioprinted tissue therapeutics.

Responsibilities

• Design, develop, and functionalize natural biomaterials and synthetic polymers that support bioprinted tissue therapeutic function, tolerance, and durability.
• Develop biomaterial strategies and hydrogel formulations that enable: 1) bioprinted therapeutic cell function and immune-protection, 2) bioprinted tissue oxygenation and vascularization, and 3) biocompatible and durable integration with host tissue implant site.
• Design and execute studies to characterize the physical and chemical properties of hydrogel biomaterials
• Provide technical domain expertise on polymer backbone, cross-linking, and stability characteristics of biomaterial-based hydrogels.
• Serve as technical lead for third party search and evaluation of biomaterials sourced for manufacturing of bioprinted tissue therapeutics.
• Work closely with biologists and engineers to customize biomaterial formulations for specific therapeutic tissue applications needs, including cell therapies for metabolic disease.
• Liaise with our manufacturing and regulatory team to develop stage-appropriate biomaterial manufacturing processes, scalable sourcing of materials, and quality assurance measures for preclinical, nonclinical safety, and clinical studies.
• Create SOPs, deliver experimental reports, support patent applications, and present experimental results to key internal and external stakeholders.
• Contribute to development of project milestones, timelines, and product deliverables in collaboration with senior R&D management and tissue therapeutic program teams.
• Maintain clear and rigorous experimental records.

QUALIFICATIONS

• PhD in chemical engineering, biomedical engineering, tissue engineering, or similar discipline. Minimum of 5 years directly related experience, with at least 3 years of industry experience preferred.
• You have hands-on experience in a lab doing polymer design, synthesis, functionalization, and processing for drug delivery, tissue engineering, cell therapeutic, or medical device applications. You have worked extensively with synthetic or natural biomaterials as well as hydrogels, developing strategies to characterize bioactivity and assure quality for therapeutic applications. Experience in bioink formulation for 3D bioprinting or testing of biomaterials in preclinical models or clinical applications in an industry setting is helpful.

WHO WE ARE

Aspect Biosystems is a Canadian biotechnology company creating bioprinted tissue therapeutics to transform how we treat disease. Our bold team of innovators and entrepreneurs have joined us from all over the globe to create a new class of regenerative medicine and work towards a future where our bioprinted tissues are used to save lives and make people healthier. We are endlessly curious and wildly passionate about what we do. Every person on our team is a key contributor to our success and is eager to roll up their sleeves to make a difference in the ever-changing world of biotech. If you are committed to making a real impact and accelerating the development of life-changing therapies, we want to hear from you!
Curious about our current perks and benefits? Learn more here.
At Aspect Biosystems, our strength has always been in our diversity. Different people, thinking differently, unified in creating a world that is better for us all. We are committed to creating an inclusive environment for everyone on our team. All aspects of employment — including the decision to hire, promote, discipline, or terminate — are based on merit, competence, performance, and business needs. We do not discriminate on the basis of race, colour, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, provincial, or local law.
If you’re interested in joining our team but don’t see a job posting that matches your experience or background, we encourage you to submit a general application to be considered for future opportunities

• Design, develop, and functionalize natural biomaterials and synthetic polymers that support bioprinted tissue therapeutic function, tolerance, and durability.
• Develop biomaterial strategies and hydrogel formulations that enable: 1) bioprinted therapeutic cell function and immune-protection, 2) bioprinted tissue oxygenation and vascularization, and 3) biocompatible and durable integration with host tissue implant site.
• Design and execute studies to characterize the physical and chemical properties of hydrogel biomaterials
• Provide technical domain expertise on polymer backbone, cross-linking, and stability characteristics of biomaterial-based hydrogels.
• Serve as technical lead for third party search and evaluation of biomaterials sourced for manufacturing of bioprinted tissue therapeutics.
• Work closely with biologists and engineers to customize biomaterial formulations for specific therapeutic tissue applications needs, including cell therapies for metabolic disease.
• Liaise with our manufacturing and regulatory team to develop stage-appropriate biomaterial manufacturing processes, scalable sourcing of materials, and quality assurance measures for preclinical, nonclinical safety, and clinical studies.
• Create SOPs, deliver experimental reports, support patent applications, and present experimental results to key internal and external stakeholders.
• Contribute to development of project milestones, timelines, and product deliverables in collaboration with senior R&D management and tissue therapeutic program teams.
• Maintain clear and rigorous experimental records