JOB DESCRIPTION

Work Location: West Hills, CA
Group: Specialty Diagnostics Group
Division: Transplant Diagnostics

EDUCATION / EXPERIENCE

PhD degree in Cell Biology, Biotechnology, Bioengineering, Biochemistry, Immunology, Genetics or a related subject area in Biological Sciences AND at least 3 years of post-graduate experience; Master’s degree in above areas AND at least 8 years of post-graduate experience

KNOWLEDGE, SKILLS AND ABILITIES

Extensive hands-on experience with WAVE and Xuri bioreactor systems.
Clear understanding of bioreactor, cell culture, cell line development and cell banking principles and practices.
Proficiency in aseptic techniques and maintaining sterile environments.
Ability to design, conduct, and interpret experiments independently.
Strong communication, documentation (organization and record-keeping), and presentation skills.
Ability to perform multi-tasks and manage priorities to meet company goals.
Strong problem-solving skills, identifying root causes, and proposing alternative approaches and feasible solutions.
Ability to work both independently and collaboratively in a group setting to meet project timeline.
Flexibility and adaptability in a highly dynamic and demanding environment.
A complete employee benefits package includes health insurance, life insurance, paid time off (PTO), life insurance, employee stock purchase plan (ESPP), etc.

Operate and optimize WAVE or Xuri bioreactor systems for cell culture applications.
Design, perform, and troubleshoot experiments involving the culture of various cell lines.
Develop and refine aseptic techniques to ensure contamination-free cultures.
Perform scale-up study studies to support process development and production.
Maintain detailed and accurate records of experiments, protocols, and results.
Analyze data and present findings to internal teams.
Collaborate with cross-functional teams to support project goals and timelines.
Conduct the preparation of technical reports, manuscripts, and presentations.
Maintain mammalian cell culture including thawing, passaging, expansion, cell banking, and inventory management.
Generate recombinant cell lines including transfection, selection, enrichment, single cell cloning, clonal expansion, and banking.
Characterize cell lines by cell viability analyzer, antigen expression by flow cytometry, cell line identity by molecular typing, and cell line sterility by mycoplasma testing.
Purify antigen or antibody. Perform biochemical and biophysical characterizations including concentration determination, SDS-PAGE, Western Blot, ELISA, and Luminex.
Perform all activities in compliance with GDP, GMP, regulatory and safety policies.