Scientist, Immunology Cell Therapy Discovery at AstraZeneca

Waltham, Massachusetts, United States -

Full Time

Start Date

Immediate

Expiry Date

20 Feb, 26

Salary

130800.0

Posted On

22 Nov, 25

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Cellular Therapy, Immunology, Immune-Mediated Diseases, In Vivo Skillset, Animal Handling, Mouse Tumor Models, Transfection, Transduction, Cell Culture, T-Cell Functional Characterization, Flow Cytometry, Drug Discovery, Teamwork, Data Assessment, Technical Instruction

Industry

Pharmaceutical Manufacturing

Description

AstraZeneca, a global leader in biopharmaceuticals, is committed to discovering and delivering innovative therapies that transform patient outcomes. We are seeking a dedicated and hands-on Scientist to join our Immunology Cell Therapy Discovery team. This role focuses on active laboratory involvement and collaboration to advance cell therapy discovery projects. The ideal candidate will demonstrate strong teamwork skills, a willingness to learn, and a humble attitude. Accountabilities • Conducts hands-on drug discovery research experiments • Works collaboratively in a matrix and fast-paced environment • Assesses and reports data with a clear understanding of its implications within the overall context of drug discovery • Maintains a proven understanding of approaches to drug discovery and applies a broader functional knowledge of the procedures used by diverse project groups to support the department where needed • Provides technical instruction to the team and allocates administrative work where possible • Ensures own work, and work of peers, is compliant with relevant internal AstraZeneca standards and external regulations Essential Skills/Experience Bachelor's degree with 3+ years of experience in a relevant scientific field or significant relevant experience and knowledge of Cellular Therapy, Immunology, and Immune-mediated Diseases from working in the life science sector. In vivo skillset including animal handling, mouse tumor models, standard routes of dosing and engraftment Experience in developing cellular therapies including CAR-T, TCR-T, and/ or TIL therapies Proficiency in transfection/transduction, expansion, and cell culture of primary human /mouse T cells and cell lines Hands-on expertise in T-cell functional characterization assays such as in vitro cytotoxicity, proliferation, cytokine measurement Proficiency with multi-parameter flow cytometry (Immunostaining, acquisition, and analysis) Desirable Skills/Experience Background in drug discovery and development in the pharmaceutical industry Advanced degree in related field At AstraZeneca, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. With one of the broadest and deepest Immunology pipelines in the industry, there are many opportunities to work with new and novel drugs. Our collaborative environment empowers us to take smart risks, challenge the norm, and learn from failures. We are united in our vision to eliminate cancer as a cause of death, making bold moves that truly improve patient outcomes. Join us in our mission to make a meaningful difference for patients around the world! The annual base pay for this position ranges from $87,200 - $130,800. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Date Posted 21-Nov-2025 Closing Date 12-Dec-2025 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Responsibilities

Conduct hands-on drug discovery research experiments and work collaboratively in a matrix and fast-paced environment. Assess and report data with a clear understanding of its implications within the overall context of drug discovery.