Scientist – In Vivo Pharmacology at Amigen

South San Francisco, California, United States -

Full Time

Start Date

Immediate

Expiry Date

24 Jul, 26

Salary

166483.2

Posted On

25 Apr, 26

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

In vivo pharmacology, Rodent handling, Dosing, Blood collection, Necropsy, Tissue fixation, Tissue embedding, Cryosectioning, FFPE sectioning, Slide preparation, Histology, Specimen orientation, Vivarium support, Cardiovascular research, Data presentation

Industry

Biotechnology Research

Description

Career Category Scientific Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Scientist – In Vivo Pharmacology – Cardiometabolic Disorders What you will do Let’s do this. Let’s change the world. In this vital role, you will work onsite at Amgen’s South San Francisco campus as part of a collaborative in vivo research team advancing discovery biology and the therapeutic development of the next generation of cardiovascular medicines. You will contribute to studies that deepen our understanding of cardiovascular disease and help push the boundaries of cardiovascular science in support of innovative drug discovery. Key Responsibilities: Conduct hands-on in vivo work in mice, including dosing, handling, health monitoring, and blood collection. Perform necropsies and collect tissues to support downstream workflows. Conduct tissue workflow activities, including tissue fixation, trimming, embedding, cry sectioning and/or FFPE sectioning, slide preparation, and sample tracking to ensure high-quality samples are delivered to downstream groups for analysis. Maintain tissue and slide quality through proper specimen orientation, labeling, handling, and section QC. Partner with scientists to execute study plans, communicate progress, and present data and results to study teams. Maintain accurate experimental records and coordinate sample flow from collection through slide preparation and handoff to downstream groups for analysis. Participate in dosing and husbandry, including occasional evening or weekend work. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The Scientist we seek is a seasoned professional with these qualifications. Basic Qualifications: Doctorate degree OR Master’s degree and 2 years of In Vivo Pharmacology experience OR Bachelor’s degree and 4 years of In Vivo Pharmacology experience Preferred Qualifications: Hands-on experience on in vivo rodent studies in an academic or industry setting. Proficiency in mouse techniques such as dosing, blood collection, and health monitoring. Demonstrated skill in necropsy and in the collection, dissection, and preservation of tissues for histologic and other downstream analyses. Familiarity with histology workflows, including tissue fixation, processing, embedding, cryosectioning, microtomy, FFPE preparation, slide preparation, and staining methods. Ability to manage sectioning workflows and prepare high-quality slides for downstream analysis. Familiarity with mouse husbandry and vivarium-based study support. Cardiovascular in vivo background is a plus. What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance. Salary Range 123,052.80USD -166,483.20 USD Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit www.amgen.com and follow us on www.twitter.com/amgen

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Responsibilities

The scientist will conduct hands-on in vivo research, including dosing, blood collection, and necropsy, to support cardiovascular drug discovery. They will also manage tissue workflows, including fixation, sectioning, and slide preparation, while maintaining accurate experimental records and presenting data to study teams.