Senior Expert Science & Technology (Oligonucleotide Chemist) at Novartis

, Basel-City, Switzerland -

Full Time

Start Date

Immediate

Expiry Date

08 Mar, 26

Salary

0.0

Posted On

08 Dec, 25

Experience

5 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Oligonucleotide Chemistry, Process Development, Synthesis Strategy, Downstream Processing, Chromatographic Processes, Nucleic Acid Chemistry, Process Engineering, Analytics, Troubleshooting, Collaboration, Research, Safety Oversight, Automated Platforms, Scalable Processes, Health Authority Documentation, PostDoc Experience

Industry

Pharmaceutical Manufacturing

Description

Job Description Summary Location: Basel, Switzerland #onsite We have a fantastic opportunity for a Oligonucleotide Chemist in our CHAD department here in Basel. Job Description Your responsibilities: Your responsibilities include, but are not limited to: Defining fit-for-purpose synthesis strategy for drug substance manufacturing and Health Authority documentation. Develop efficient and scalable oligonucleotide processes on relevant projects within Novartis portfolio across different scales. Be part of the Oligo chemist / engineering team to develop and optimize syntheses used in process R&D. Investigate various approaches for oligonucleotide preparation and evaluate their potential by applying cutting-edge automated platforms. Ensuring utilization of state-of-the-art technologies and science. Efficient use of lab resources. Maintaining oversight on process safety. Co-leading the process transfer to pilot plants. Serving as consultants for troubleshooting during campaigns. Collaborating with internal and external stakeholders or partners Collaborate with diverse experts in the areas of Nucleic Acid Chemisty, Process Chemistry, Process Engineering and Analytics. What you’ll bring to the role: A completed PhD in Organic Chemistry, or Chemical engineering PostDoc with a focus on oligonucleotides processes. Experience in developing platform synthesis concepts for oligonucleotides Experience in process development using state of art oligo synthesizers. Experience in downstream processing including TFF and chromatographic processes An excellent track record of original research and extensive experience in using “state of the art” technologies. Fluency in English Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Skills Desired Improving the lives of people living with disease takes more than innovative science. It takes a focus on the needs of people and a community committed to meeting them. It takes a team of people like you. Working together. Learning together. Thriving together. Discover how you can join us in changing people’s lives. In the context of China Cross-Border Data Transfer (CBDT) policy, if you need to apply for a position in China, please go to the local Recruiting System TaleNov .

Responsibilities

The role involves defining synthesis strategies for drug manufacturing and optimizing oligonucleotide processes. The candidate will collaborate with various experts and ensure the efficient use of lab resources while maintaining process safety.