Senior Expert Science & Technology - PRD Chemist at Novartis

Basel, Basel-City, Switzerland -

Full Time

Start Date

Immediate

Expiry Date

29 Jul, 26

Salary

0.0

Posted On

30 Apr, 26

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Chemical synthesis, Process development, Bioconjugation, Antibody-oligonucleotide conjugates, Chemical modification, GMP, Experimental design, Data interpretation, Manufacturing instructions, Cross-functional collaboration, Nucleotide drugs, Process documentation, DoE tools, Technical writing, Scientific exchange

Industry

Pharmaceutical Manufacturing

Description

Job Description Summary Location: Basel, Switzerland #onsite Role purpose: The position is within the Global Technical R&D department of Global Drug Development. Within this organization Chemical & Analytical Development (CHAD) plays an essential role in the development of processes for manufacturing and analysis of Antibody-Oligonucleotide conjugates (AOCs). Job Description Your Responsibilities: With your strong expertise and creativity in chemical synthesis and process development, you take a leading role in setting up future chemistry and manufacturing pathway for Antibody-Oligonucleotide-Conjugates (AOCs) and other complex constructs. You will be a key contributor to engage and ensure adequate support and knowledge transfer for Novartis BD&L activities focussing on bioconjugation chemistry and manufacturing processes. In our labs, your experimental designs will be executed and allow you to interpret and report data and results Further, he/she coordinates and ensures timely availability and transfer of manufacturing instructions to pilot plant within Chemical & Analytical Development (CHAD) or CMOs. As a core member of cross-functional teams, you collaborate closely with our internal and external partners to ensure timely and quality delivery of new nucleotide drugs to our patients Further, you will provide relevant process documentation in support of filing of dossiers. You will also actively participate in scientific exchange groups within Novartis and Academia and maintain excellent collaboration with our customers. Minimum Requirements: Education: We are looking for candidates with PhD and PostDoc in organic chemistry preferably with specialization in the field of bio-conjugation or chemical modification of fermentation products. Experience and Expertise: In addition, the ideal candidate would have the following professional experience: Recent and proven knowledge in space of chemical bioconjugation or chemical modification of fermentation products, e.g. Antibody-Drug Conjugations, etc. or other complex molecular structures is an essential requirement 2-5 years experience in synthesis/ chemical process development is a strong requirement, experience in piloting experience under GMP is a benefit Independent and self-motivated workstyle with team orientation and adequate communication style is an essential requirement Advanced knowledge of software and computer tools such as Office package, DoE tools, etc. is desirable Language Skills: Adequate knowledge of English language is a requirement (oral and written), German and other language skills are beneficial. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Skills Desired Improving the lives of people living with disease takes more than innovative science. It takes a focus on the needs of people and a community committed to meeting them. It takes a team of people like you. Working together. Learning together. Thriving together. Discover how you can join us in changing people’s lives. Novartis is aware of employment scams which make false use of our company name or leader’s names or recruiter’s names to defraud job seekers. Novartis does not make job offers without interview and never asks candidates for money. If you have encountered a job posting or been approached with a job offer that you suspect may be fraudulent, we strongly recommend you do not respond, send money or personal information. In the context of China Cross-Border Data Transfer (CBDT) policy, if you need to apply for a position in China, please go to the local Recruiting System TaleNov .

Responsibilities

The role involves leading the development of manufacturing pathways for Antibody-Oligonucleotide conjugates and ensuring effective knowledge transfer for bioconjugation processes. You will coordinate with pilot plants and cross-functional teams to deliver high-quality nucleotide drugs while managing process documentation for regulatory filings.