ABOUT SHIELDS PHARMA INC.

Shields Pharma Inc. is a Health Canada approved GMP organization located in Markam, Ontario.
We offer Laboratory R&D and QC testing services as well as production and formulation of certain psychedelic therapeutics for treatment of certain mental health disorders such as anxiety, depression, obsessive-compulsive disorder, PTSD, and problematic substance.
Shields Pharma Inc. is an equal opportunity employer committed to diversity and inclusion for everyone. We are continuously looking for smart-minded, skilled, qualified, experienced, independent, reliable, and detail-oriented candidates to join our successful team.
Our people are at the heart of everything we do.

You can count on;

• Safety as our first core value,
• Integrity,
• Accountability, and
• Continuous Training and skill development.

Position Title: Senior Laboratory Analyst – LC-MS/MS & GC-MS/MS (Nitrosamines Testing)
Reports To: Director of Laboratory Operation

QUALIFICATIONS & EXPERIENCE

Work Authorization: Must be a Canadian citizen or permanent resident with valid work permit.
Location: Must reside in Canada, preferably Toronto or surrounding areas.

EDUCATION:

• M.Sc. in Chemistry, Analytical Chemistry, Pharmaceutical Sciences (minimum 3 years of experience)
• OR B.Sc. in a related discipline (minimum 5 years of experience)

TECHNICAL SKILLS & KNOWLEDGE:

• Proven hands-on experience with LC-MS/MS, GC-MS/MS, HPLC, and ICP-MS.
• Strong background in nitrosamines risk assessment and testing.
• Proficient in method development, validation, stability testing, and instrument qualification.
• Knowledgeable in USP, BP, EP, JP pharmacopeial methods and specifications.
• Strong understanding of cGMP, GDP, GXP, ICH, FDA CFR 211, and ALCOA+ principles.

ABOUT THE ROLE:

Shields Pharma is seeking a Senior Laboratory Analyst with proven expertise in LC-MS/MS and GC-MS/MS, particularly in the analysis of nitrosamine impurities. The ideal candidate will support both R&D and Quality Control (QC) activities, ensuring compliance with all applicable regulatory guidelines and standards.
In addition, the Senior Analystis responsible for conducting method development and validation, method transfer, assay and impurity analysis by utilizing HPLC, LC/MS, GC-Headspace, GC/MS, and ICP-MS, projects according to the schedule established by following the procedures and adhering to Good Manufacturing Practices (GMP), GXP, and good laboratory practices.
This is a hands-on analytical role, ideal for someone passionate about working in a fast-paced pharmaceutical laboratory environment, who thrives on solving analytical challenges and delivering high-quality data in support of drug development and production.

KEY RESPONSIBILITIES:

• Perform analysis of nitrosamine impurities using LC-MS/MS and GC-MS/MS methods in APIs, excipients, and finished products.
• Perform all works in accordance with all established company policies, protocols and procedures, and governing regulatory, GMP compliance, and safety guidelines
• Conduct method development, validation, transfer, cleaning validation, and stability studies.
• Operate, troubleshoot, and maintain analytical instrumentation including HPLC, UPLC, GC-Headspace, GC-MS, LC-MS/MS, and ICP-MS.
• Ensure all work complies with GMP, GXP, GDP, and safety guidelines.
• Maintain accurate and compliant laboratory documentation in line with Good Documentation Practices (GDP) guidelines.
• Perform and support investigations (OOS, OOT, deviations), and prepare necessary documentation (SOPs, CAPAs, etc.).
• Train and provide scientific guidance to junior analysts.
• Collaborate cross-functionally with R&D and QC teams to meet project timelines.
• Support and participate in regulatory inspections (e.g., Health Canada, FDA), and client audits.
• Ensure lab supply inventory is maintained and oversee vendor-related activities when needed.
• Review peer reports and analytical data for accuracy and compliance.