JOB SUMMARY:

Vertex is seeking a talented individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families, and society.
As a Senior Manager and member of our Global HEOR team, your primary responsibility will be to execute on the tactical plan to generate evidence supporting the value proposition of Vertex’s CF portfolio of assets. You will contribute to each stage of the development, launch and post-launch phases.
This Senior Manager will report to the Director HEOR, CF. The role will be hybrid, based in Vertex’s Boston office in the Seaport District.

MINIMUM QUALIFICATIONS:

• An advanced degree (e.g., PhD, PharmD, MPH, MS) with an educational focus in a relevant discipline in the areas of health economics or outcomes research
• Typically requires 5+ years of combined consulting and or biopharmaceutical industry experience in health economics and outcomes research, or the equivalent combination of education and experience
• Technical expert in HEOR able to formulate and lead complex research projects ensuring that study conduct is technically and scientifically rigorous, reflects best HEOR practices and managed to timelines and budgets
• Experience executing observational research studies (prospective and/or retrospective)
• Strong attention to detail and quality focus
• Exceptional written and verbal communication skills along with the ability to effectively present technical data and complex concepts to diverse audiences
• A strong track record of publishing in peer reviewed scientific journals and presenting at scientific meetings
• A track record of success functioning in dynamic, matrix environments with the ability to multi-task seamlessly, balance competing priorities, and communicate proactively with key stakeholders
• Comprehensive understanding of the legal and regulatory environment of the pharmaceutical industry, with spotless history of compliance and ethical workplace conduct

• Support execution of HEOR evidence generation studies, including prospective and retrospective observational studies, systematic literature reviews, clinical outcome assessment measure development and validation studies, cost-effective analyses, and budget impact models, as needed, to support the asset value
• Effectively lead external research partners to ensure robust scientific methods are applied to study design and execution and in compliance with all local regulations; be accountable for study design, data analysis and the quality of the evidence produced
• Support development of product value proposition/value messaging and co-lead development of robust Global launch deliverables (e.g., global value dossier)
• Provide excellent project management, supporting study team and monitoring external vendors to ensure studies are delivered on time and within budget
• Develop presentations to communicate complex HEOR evidence to cross-functional internal audiences
• Clearly communicate study findings to internal and external audiences; lead conference submissions and peer-reviewed publications and ensure evidence is shared appropriately with key stakeholders
• Act as subject matter expert in HEOR evidence generation across the Global organization