Senior Principal Scientist, Lab Head, Type 2 Immunology at Sanofi Aventis US LLC

Cambridge, Massachusetts, United States -

Full Time

Start Date

Immediate

Expiry Date

17 Jan, 26

Salary

212333.0

Posted On

19 Oct, 25

Experience

10 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Immunology, Drug Discovery, Team Leadership, Scientific Communication, Assay Development, Collaboration, Strategic Thinking, Problem Solving, Data Analysis, Innovation, Mentoring, Translational Immunology, Multi-Omic Technologies, Cell-Based Assays, Molecular Techniques, Imaging

Industry

Pharmaceutical Manufacturing

Description

Job Title: Senior Principal Scientist, Lab Head, Type 2 Immunology Location: Cambridge, MA About the Job Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. Sanofi is seeking an accomplished, visionary, and strategic scientific leader to join our Immunology & Inflammation Research Therapeutic Area as a Lab Head at the Director level. This pivotal role will be instrumental in shaping and advancing our innovative portfolio aimed at discovering and developing transformative therapies for immune-mediated diseases. The successful candidate will lead a dedicated research laboratory, providing scientific and strategic leadership, fostering a culture of high performance and innovation, and driving drug discovery programs from novel target identification through to preclinical development. This position demands deep expertise in Type 2 immunology, a strong track record of scientific achievement, and proven leadership capabilities in a drug discovery setting. The successful candidate will have an opportunity to leverage Sanofi’s vast Drug Discovery Toolbox and application of AI, at scale, to contribute significantly to the research efforts directed towards developing new therapeutics. Research activities will be broad with the ideal candidate having strong technical expertise in both murine and human immunology. The position will initially support our pre-clinical portfolio, supporting the generation of high quality, robust data packages for transition to early clinical development teams across dermatology, gastroenterology, respiratory and rheumatology. This role will involve guiding matrix and local teams in in partnership with our Discovery Platform colleagues as well as teams in Development, Medical Affairs and Commercial to drive our research directions and maximize the value of these innovations. The successful candidate will have an opportunity to leverage Sanofi’s vast technical toolbox and application of AI, at scale, to contribute significantly new and existing projects. Research activities will be broad with the ideal candidate having strong technical expertise in both murine and human immunology. A successful candidate should be experienced with novel assay development (both in vitro and in vivo) and have a track record in immunological and disease pathway exploration. Technical expertise in imaging, cell-based assays, molecular techniques (including single cell approaches), and multi-omic based technologies will be necessary to further our research ambitions. The candidate should be able to scientifically lead and execute research work, analyze, and present data, and have an ability to utilize excellent technical, written, and oral communication skills (across both expert and non-expert audiences), and effectively collaborate in a team environment. Experience with mentoring junior members of teams is preferable. A successful candidate should be curious in exploring new paths for scientific discoveries and bold in proposing creative experimental designs and ideas. We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started? Main Responsibilities: Scientific and Strategic Leadership Provide expert scientific vision, strategic direction, and operational leadership for a research laboratory focused on identifying and validating novel therapeutic targets and advancing drug discovery programs in immunology and inflammation. Team Leadership and Development Lead, mentor, and develop a team of scientists and researchers, fostering a culture of scientific excellence, innovation, collaboration, and urgency. Manage team performance and resource allocation Portfolio Delivery Drive the progression of immunology projects from target discovery and validation through to candidate selection and IND-enabling studies. Ensure robust, data-driven decision-making and timely delivery of milestones. Cutting-Edge Research Champion and implement innovative scientific approaches and cutting-edge technologies to address critical questions in immunology and enhance our drug discovery capabilities. Stay at the forefront of scientific advancements in the field. Cross-Functional Collaboration Build and maintain strong collaborative relationships with other research teams, therapeutic areas, platform groups (e.g., molecule discovery teams, target discovery and systems biology teams, translational medicine), and clinical development functions to ensure seamless project transitions and strategic alignment. External Engagement and Innovation Sourcing Establish and manage external collaborations with academic institutions, biotechnology companies, and key opinion leaders to access novel science, technologies, and therapeutic opportunities. Scientific Communication and Visibility Ensure high-quality internal and external scientific communication, including presentations at international conferences, publications in peer-reviewed journals, and contributions to patent filings and regulatory submissions. Represent Sanofi at external scientific forums. Resource Management Effectively manage laboratory resources, including budget, equipment, and personnel, to ensure optimal productivity and scientific output. Contribution to Therapeutic Area Strategy Actively contribute to the overall strategy and portfolio prioritization within the Immunology & Inflammation Research Therapeutic Area. About You Basic Qualifications: PhD with 10+ years of experience Contribution to Therapeutic Area Strategy Actively contribute to the overall strategy and portfolio prioritization within the Immunology & Inflammation Research Therapeutic Area. Demonstrated track record of outstanding scientific achievement in immunology evidenced by high-impact publications, patents, and successful advancement of drug discovery programs. Proven experience in leading, managing, and mentoring a team of scientists, with a clear ability to inspire and develop talent. Deep expertise in one or more areas of immunology (e.g., autoimmunity, inflammation, specific immune cell biology, signaling pathways) and a broad understanding of the field. Extensive experience in target identification, validation, and preclinical drug discovery across various modalities (e.g., biologics, small molecules). Strong strategic thinking, problem-solving, and decision-making abilities. Excellent communication, interpersonal, and presentation skills, with the ability to influence and engage scientists and leaders across a complex organization. Demonstrated ability to work effectively in a matrixed environment and lead cross-functional teams. Preferred Qualifications: Experience in successfully leading drug discovery programs that have progressed to clinical development. Expertise in translational immunology and the application of human immunology insights to drug discovery. Experience with novel therapeutic modalities in an immunology context. Established network within the academic and industry immunology community. Experience in managing external collaborations and alliances. Why Choose Us? Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. #GD-SA #LI-SA #LI-Onsite #vhd Pursue progress, discover extraordinary Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com! US and Puerto Rico Residents Only Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. North America Applicants Only The salary range for this position is: $147,000.00 - $212,333.33 All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK. Global Terms & Conditions and Data Privacy Statement Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi - YouTube

Responsibilities

The successful candidate will provide scientific and strategic leadership for a research laboratory focused on drug discovery in immunology. They will lead a team of scientists, drive project progression, and foster collaboration across various functions.