Senior/Principal Scientist, Oligonucleotide Therapeutics, BioArctic at Search4s Dustgoat AB

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Full Time

Start Date

Immediate

Expiry Date

14 Feb, 26

Salary

0.0

Posted On

16 Nov, 25

Experience

5 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Molecular Biology, Molecular Genetics, Biochemistry, Pharmacology, Oligonucleotide Design, Bioinformatic Analysis, Gene Expression Analysis, ASO Technologies, siRNA Technologies, Cell-Based Assays, Tissue-Based Assays, Conjugation Chemistry, Analytical Skills, Communication Skills, Collaboration, Project Management

Industry

Description

In this role, you will establish and drive BioArctic’s growing initiative within oligonucleotide therapeutics. You will be our internal expert in the field, taking part in drug development programs, contributing both strategically and scientifically. This is a dynamic role combining concept development with coordination of internal and external activities, and hands on data analysis and documentation. Depending on the candidate, experimental work can also be required. The focus is on the design, analysis, and evaluation of therapeutic oligonucleotides, as well as integrating these technologies into BioArctic’s research portfolio. You will work in cross-functional project teams and collaborate closely with external CROs. The position is in Stockholm, full-time, open ended, with BioArctic as employer. Key Responsibilities Participate in drug development programs, driving scientific strategy and execution Lead and perform design and analyses of oligonucleotides such as ASO and siRNA using bioinformatic tools Participate in development of conjugation strategies (e.g. linker, peptide, ASO–antibody conjugates) and detailed characterization Assess gene expression (qPCR, NGS) and cell- and tissue-based analyses. Evaluate target and off-target effects Plan, coordinate, and follow up work performed by external CROs Contribute to project strategies and cross-functional scientific discussions Qualifications Ph.D. in molecular biology, molecular genetics, biochemistry, pharmacology, or related field Deep understanding of ASO and siRNA technologies Proven experience in oligonucleotide design and bioinformatic analysis Experience in analysing ASO or siRNA effects in cell- and tissue-based assays (on target and off-target) Solid understanding of gene expression analysis (qPCR, NGS) Experience from biotech or pharmaceutical industry, including sponsorship of CROs or equivalent. Excellent communication skills in English Meriting qualifications In vivo experience with ASO or siRNA Familiarity with research on brain disorders Experience in conjugation chemistry, especially ASO–antibody conjugates Swedish language skills Who You Are Analytical and solution-oriented Communicative and confident in a leading scientific role Proactive and independent, yet collaborative Structured and detail-conscious without losing momentum Application Apply as soon as possible – interviews are held continuously. For questions about the role, please contact Anna Rennermalm, Search4S, anna@search4s.se, +46 70 794 20 05 Last application date: Dec 14th 2025 About BioArctic BioArctic is an innovative Swedish biopharma company focused on neurodegenerative disease research, such as Alzheimer’s disease, Parkinson’s disease and ALS. BioArctic’s research has resulted in the world’s first fully approved disease-modifying drug against Alzheimer’s disease. The company has also developed the BrainTransporter™ technology, that has the possibility to improve the result of treatment against diseases of the brain. BioArctic’s head office is located in Stockholm Sweden, and the company has more than 130 employees. Learn more about the company on www.bioarctic.com

Responsibilities

You will participate in drug development programs, driving scientific strategy and execution. The role involves leading the design and analysis of therapeutic oligonucleotides and coordinating work with external CROs.