ABOUT US

Dimitrios Anastasiou’s laboratory investigates the fundamental mechanisms that regulate healthy cellular and whole-body metabolism and how disruption of these mechanisms contributes to cancer development and metabolic liver disease. To this end, the lab uses a multidisciplinary approach that includes mouse models of liver disease and cancer, metabolomics, stable isotope-labelled tracers to measure metabolic activities in vivo, computational modelling (through expert collaborators) and protein biochemistry.

The role of a Principal Laboratory Research Scientist is diverse and rewarding. The role covers a wide range of different functions and allows for continuity of lab operations. The role offers support to one or more scientific projects or programmes. Typical activities include: • Independently undertaking own research projects, designing, and executing experiments in consultation with the group leader. • Collaborating with other lab members on research projects. • Providing experimental or technical support to other lab members. • Providing technical expertise and input for the development, optimisation and troubleshooting of relevant and novel methodologies. • Initiating and managing long-term investigations and collaborations with other researchers. • Participating in academic activities, including group meetings and journal clubs, seminars, and scientific meetings. • Writing up findings for publication and completing revisions. • Organisation and management of the laboratory, including maintaining laboratory databases, ordering of laboratory supplies, monitoring budgets, and routine maintenance of laboratory equipment. • Training and supervising other lab members in key techniques and protocols, lab operations, and equipment use. • Liaising with Science Operations and attending key quadrant meetings. • Writing risk assessments and SOPs and providing safety guidance to lab members.