BeiGene, Ltd. has proposed to change its name to BeOne Medicines Ltd. The new name is subject to shareholder approval and, once approved, use of the name will be phased in over 2025. There may be instances where “BeiGene” or “BeOne” are used to describe the company during this transition period. BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.
General Description:
We are seeking a highly motivated and detail-oriented Senior Scientist to lead the development, validation, and execution of immunohistopathology (IHC) assays in a clinical biomarker setting. The successful candidate will be instrumental in supporting clinical trials and translational research through the generation of high-quality, tissue-based biomarker data. This role involves close collaboration with pathologists, clinical teams, and CDx development functions to ensure that assays are robust, reliable and fit-for-purpose to support various oncology and non-oncology pipelines.

Essential Functions of the job:

• Lead strategic design and implementation of the new IHC workflow.
• Design, develop and optimize IHC assays for biomarker detection in fresh and FFPE tissue samples.
• Select and validation antibodies, detection systems, and staining protocols to ensure assay specificity and sensitivity.
• Validate IHC-based assays and execute clinical sample analysis. Perform and oversee IHC staining and imaging; coordinate with pathologists for interpretation and scoring of results
• Author and review method development and validation protocols, reports, and SOPs.
• Ensure quality control, data integrity, and timely delivery of analytical results.
• Contribute to cross-functional project teams supporting clinical trial biomarker strategies
• Maintain accurate lab records and mentor junior scientists.

Supervisory Responsibilities:

• This role is initially an individual contributor. May supervise lab scientists as the team grows.

Computer Skills:
Proficiency in general software such as Microsoft Office (Word, Excel, PowerPoint), Outlook, Zoom, Teams as well as IHC task-related systems.

Other Qualifications:

• Ph.D. with 2+ years or M.S. with 4+ years of hands-on IHC assay experience in a clinical, translational or regulated environment
• Strong background in IHC assay development and validation using fresh or FFPE tissues.
• Familiarity with automated staining platforms (e.g. Ventana, Leica, Dako) and image analysis software (e.g. HALO, QuPath).
• Understanding of clinical biomarker strategies and regulatory requirements for exploratory or filling purposes.
• Demonstrated analytical and problem-solving skills with the ability to think critically.
• Excellent communication, organization and project management skills.
• Experience in lab automation, electronic laboratory notebook (ELN), laboratory information management system (LIMS) and initial lab workflow set-up is a plus.

Education Required:
PhD in Pathology, Molecular Biology, Immunology, or related field with 2+ years of relevant experience (or MS with 4+ years).
Travel: Under 10%
Global Competencies

When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self-Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results-Oriented
• Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

Salary Range: $118,000.00 - $158,000.00 annually
BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeiGene, Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.
We are proud to be an equal opportunity employer and we value diversity. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need.

Essential Functions of the job:

• Lead strategic design and implementation of the new IHC workflow.
• Design, develop and optimize IHC assays for biomarker detection in fresh and FFPE tissue samples.
• Select and validation antibodies, detection systems, and staining protocols to ensure assay specificity and sensitivity.
• Validate IHC-based assays and execute clinical sample analysis. Perform and oversee IHC staining and imaging; coordinate with pathologists for interpretation and scoring of results
• Author and review method development and validation protocols, reports, and SOPs.
• Ensure quality control, data integrity, and timely delivery of analytical results.
• Contribute to cross-functional project teams supporting clinical trial biomarker strategies
• Maintain accurate lab records and mentor junior scientists

Supervisory Responsibilities:

• This role is initially an individual contributor. May supervise lab scientists as the team grows