Senior Scientist, CAR Screening and Lead Selection, Cell & Genetic Medicine at Johnson Johnson
Cambridge, Massachusetts, USA -
Full Time


Start Date

Immediate

Expiry Date

17 Oct, 25

Salary

169050.0

Posted On

18 Jul, 25

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

No

Skills

Bench Work, Consideration, Spotfire, Panel Design, Support Center, Data Analysis, Color, Visualization, Presentation Skills, Flow Cytometry, Immunology, Cell Biology, Disabilities, Sample Preparation, Graphpad Prism

Industry

Information Technology/IT

Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

QUALIFICATIONS:

  • PhD in immunology, cell biology, or a related field with 2+ years of relevant industry or postdoctoral experience; OR a BS or MS with 4-6 years of experience will also be considered.
  • Extensive hands-on experience with multiparameter flow cytometry, including panel design, sample preparation, acquisition, and data analysis.
  • Proficiency in IncuCyte-based assays or comparable real-time cytotoxicity platforms.
  • Demonstrated expertise using ELN systems for experimental documentation, experience with Benchling a plus.
  • Advanced skills in data analysis and visualization using GraphPad Prism, Spotfire or similar software.
  • Strong problem-solving skills and the ability to independently drive projects while working collaboratively.
  • Excellent written and verbal communication and presentation skills.
  • This is an on-site lab-based role; candidates must be comfortable with extensive bench work and collaborative team science.
    Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected vertebras and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
    Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center ( ra-employeehealthsup@its.jnj.com ) or contact AskGS to be directed to your accommodation resource.
Responsibilities

PURPOSE:

We are seeking a highly motivated and technically skilled Senior Scientist to join our CAR Screening and Lead Selection team focused on advancing next-generation cell therapies. The Senior Scientist will design, execute, and analyze in vitro assays to characterize CAR-T candidates, supporting data-driven decisions that drive pipeline progression. This role offers the opportunity to work cross-functionally in a dynamic, fast-paced environment with cutting-edge technologies.

RESPONSIBILITIES:

  • Design, perform, and troubleshoot complex in vitro assays, including flow cytometry-based immunophenotyping and functional assays to evaluate CAR-T activity.
  • Develop and execute IncuCyte-based cytotoxicity assays to assess cell killing and persistence.
  • Maintain meticulous records of experimental design, data, and analysis using Benchling electronic lab notebook (ELN).
  • Analyze and visualize complex datasets using GraphPad Prism and other visualization tools; clearly communicate results in team meetings and reports.
  • Collaborate closely with colleagues in discovery, process development, and therapeutic area teams to align priorities and share data.
  • Contribute to experimental design discussions and provide technical guidance to junior team members.
  • Ensure laboratory operations follow best practices for safety, data integrity, and reproducibility.
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