Senior Scientist I – Critical Reagents at B2S Life Sciences LLC

Franklin, Indiana, United States -

Full Time

Start Date

Immediate

Expiry Date

14 May, 26

Salary

0.0

Posted On

13 Feb, 26

Experience

10 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Protein Conjugation Chemistry, Protein Purification, Biochemical Characterization, Biophysical Characterization, Experiment Design, Troubleshooting, Data Compilation, Technical Writing, GXP Compliance, Methodology Development, Literature Searching, Laboratory Equipment Maintenance, Analytical Skills, Problem Solving, Oral Communication, Written Communication

Industry

Biotechnology Research

Description

Description We are seeking a highly skilled and motivated Senior Scientist specializing with Biochemistry/Chemistry background to join B2S Critical Reagents Team Umbrella. The ideal candidate will play a key role in diligent design, generation, and characterization of critical reagents directly to the advancement of large molecule bioanalytical pipelines. Position Summary: The Senior Scientist I – Critical Reagents is responsible for the generation, characterization, and lifecycle management of custom critical reagents to support the development of robust, regulated bioanalytical assays for large-molecule biotherapeutics. Critical reagents include well-characterized polyclonal and monoclonal antibodies, recombinant proteins, conjugated proteins and peptides, gene therapy vectors, oligonucleotides, and critical reagent kits. This position offers an exciting opportunity to lead and collaborate within a multidisciplinary scientific environment, contributing to innovation, assay robustness, and scientific excellence across the development lifecycle of large-molecule biotherapeutics. Key Responsibilities. Serves as a Scientist/Principal Scientist for clients’ projects. Performs a variety of protein conjugation chemistry, protein purification activities and downstream biochemical/bioanalytical and biophysical characterization methodologies. Able to design, execute, trouble shoot experiments associated with critical reagents generation and /or characterization with minimum supervision. Compiles scientific data (including analysis and technical writing) and able to present data in an intelligible format suitable for a professional audience. Able to train junior level scientists. Reports and treats data with prominent level of integrity and ethics. Complies with application able regulations (GXP); maintains proper records in accordance with standard operating procedures (SOPs) and policies; independently designs and performs scientific experiments with a pre-defined goal including developing new methodologies, protocols, and/or test procedures that contribute to core group research goals and reflect expert knowledge. Independently apply basic scientific principles, performs literature searches, attends scientific meetings, and keeps up to date on literature in the biotherapeutic bioanalysis field. Maintains laboratory equipment, as needed. Other duties as assigned Competencies: Quality and Quantity – Demonstrates accuracy and thoroughness; Looks for ways to improve and promote quality; Applies feedback to improve performance; Monitors own work to ensure quality; Meets productivity standards; Completes work in timely manner; Strives to increase productivity; Works quickly but efficiently. Analytical - Synthesizes complex or diverse information; Collects and researches data; Uses intuition and experience to complement data; Designs workflows and procedures. Safety and Security – Observes safety and security procedures; Determines appropriate action beyond guidelines; Reports potentially unsafe conditions; Uses equipment and materials properly. Problem Solving – Identifies and resolves problems in a timely manner; Gathers and analyzes information skillfully; Develops alternative solutions; Works well in group problem solving situations; Uses reason even when dealing with emotional topics. Oral and Written Communication – Speaks clearly and persuasively in positive or negative situations; Listens and gets clarification; Responds well to questions; Demonstrates group presentation skills; Participates in meetings. Requirements Education Ph.D. degree in biochemistry, chemistry or related discipline with related experience in biology/chemistry techniques is required. M.S. degree in biochemistry, chemistry or a related discipline, 10+ years with related experience in biology/chemistry techniques is required. Experience Hands-on experience with protein purification methodologies using various chromatography techniques. Proficiency in basic protein characterization techniques such as ELISA, SDS-PAGE, analytical chromatography techniques [E.g. SEC, NP/RP – HPLC, ion exchange methodologies] Optional Technical Skills: Experience or familiarity with protein and peptide conjugation techniques, including site-specific and non-site-specific labeling approaches (e.g., NHS-ester, maleimide, and click-chemistry-based conjugations) for use in regulated bioanalytical assays. Optional Technical Skills: BLI/SPR or capillary electrophoresis [CE-SDS, cIEF]; or familiarity with protein stability profiling techniques [DLS/SLS/ DSF etc]. Strong communication and collaboration skills, with the ability to work effectively with internal teams, external partners, and key stakeholders. Demonstrated organizational skills with exceptional attention to detail and a high degree of precision. Proven ability to thrive in a fast-paced, dynamic, and highly multitasking environment while consistently delivering against objectives. Excellent critical-thinking, problem-solving, and analytical skills, with the capability to design, execute, and interpret complex experiments and datasets. Ability to work independently, manage multiple priorities, and deliver high-quality results under tight timelines and deadlines. Physical Demands Ability to stand less than 1/3 of the time. Ability to walk less than 1/3 of the time. Ability to sit more than 2/3 of the time. Ability to talk or hear from 1/3 to 2/3 of the time. Ability to lift 20 lbs. less than 1/3 of the time. Work Environment The work environment is in an office/laboratory environment. Travel up to 1-5% percent of the time. Frequent use of a computer is necessary. This position requires working independently, as well as part of a team. While performing the duties of this job the noise level in the work environment is usually moderately loud and has moderate temperatures. Personal protective equipment is required to be worn in designated lab areas: closed-toed shoes, laboratory coat, safety goggles, and gloves. This position requires the use of all general office equipment. Benefits Paid time off (vacation, holidays, sick) Medical/dental/vision insurance 401(k) to eligible employees

Responsibilities

The Senior Scientist I is responsible for the generation, characterization, and lifecycle management of custom critical reagents, such as antibodies and recombinant proteins, to support robust bioanalytical assays for large-molecule biotherapeutics. Key duties include performing protein conjugation chemistry, purification, various characterization methodologies, and compiling/presenting scientific data.