Senior Scientist Medicinal Chemistry at argenx

Ghent, Flanders, Belgium -

Full Time

Start Date

Immediate

Expiry Date

08 Mar, 26

Salary

0.0

Posted On

08 Dec, 25

Experience

10 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Medicinal Chemistry, Drug Discovery, Small Molecules, Peptide Therapeutics, Collaboration, Data Management, Communication, Problem Solving, AI, Machine Learning, Computational Chemistry, ADME/Tox, Pharmacology, Initiative, Synthesis, Project Management

Industry

Biotechnology Research

Description

Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back. argenx is preparing for multi-dimensional expansion to reach more patients through a rich pipeline of differentiated assets, led by VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases. We are building a new kind of biotech company, one that maintains its roots as a science-based start-up and pushes our commitment to innovate across all corners of our business. We strive to inspire and grow our company, our partnerships, our science, and our people, because when we do, we deliver more for patients. About the role Argenx is establishing a new department dedicated to small molecule and peptide drug discovery. We are seeking a Senior Scientist in Medicinal Chemistry to play a pivotal role in shaping this capability and advancing preclinical projects. This position offers the opportunity to influence strategy, drive innovation, and deliver high-quality drug candidates that make a real impact. This position is based at our facility in Zwijnaarde (Ghent), and expects on-site presence. Key Responsibilities Lead Discovery Projects: Partner with lead biologists to progress programs from hit identification through to clinical candidate nomination, ensuring timely delivery of high-quality candidates. Design and Optimise Molecules: Collaborate with CROs and expert consultants to design novel compounds addressing identified challenges and improving candidate profiles. Cross-Functional Collaboration: Work closely with internal experts in computational chemistry, ADME/Tox, IP, CMC, and pharmacology to integrate multidisciplinary insights. Innovation & Technology: Stay at the forefront of developments in small molecule and peptide therapeutics. Champion the use of AI, machine learning, and in silico approaches to accelerate design–make–test–analyse cycles. Data Management: Establish efficient workflows for capturing, integrating, and analysing data from multiple partners. Communication: Provide clear updates on progress, challenges, and solutions to stakeholders and project teams. Profile PhD (or equivalent) in a relevant chemical science, with 8+ years of experience in biotech or pharma. Proven track record in design and synthesis of small molecules, with experience advancing projects to preclinical development. Ability to work independently and collaboratively within a team. Excellent communication skills, capable of presenting complex scientific concepts to diverse audiences. Fluent in written and spoken English to ensure clear and effective information exchange. Demonstrated ability to take initiative and address challenges proactively. Dynamic and practical problem-solving approach with a focus on delivering tangible results. Offer The opportunity to establish a new role within the organization, contributing to shaping its future direction. A competitive salary package accompanied by comprehensive benefits. Working in a human-sized, dynamic, rapidly growing biotech company, providing an engaging work environment. #LI-onsite At argenx, all applicants are welcomed in an inclusive environment. They will receive equal consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other applicable legally protected characteristics. argenx is proud to be an equal opportunity employer. Before you submit your application, CV or any other personal details to us, please review our argenx Privacy Notice for Job Applicants to learn more about how argenx B.V. and its affiliates (“argenx”) will handle and protect your personal data. If you have any questions or you wish to exercise your privacy rights, please contact our Global Privacy Office by email at privacy@argenx.com. argenx is a global immunology company dedicated to improving the lives of people suffering from severe autoimmune diseases. Through our rich pipeline of first-in-class therapies, led by VYVGART®, we are accelerating progress toward our bold 2030 vision: to reach 50,000 patients and transform the landscape of autoimmune treatment. Our innovation mission combines with meaningful work and endless opportunities for growth to create once-in-a-career experiences. argonauts work in locations around the globe including Belgium, Boston, Japan and Amsterdam. There's more to discover at argenx, where our passion inspires bold possibility. argenx honors the terms of our written agreements with the recruiting and staffing agencies that we retain and contract with to assist us with talent searches and other recruiting needs. Accordingly, all resumes and referrals that recruiting and staffing agencies proactively share with argenx that (i) were not solicited or requested by argenx’s internal Talent Acquisition team and (ii) were sent in the absence of a valid, written agreement between argenx and the firm, recruiter, or agency, may be pursued by argenx and are ineligible for payment of referral or other fees. We encourage you to be cautious of recruiting scams and fictious communications that pretend to be from argenx employees. These scams are designed by fraudsters to get personal information (e.g., social security numbers, bank account information, dates of birth), money or payments from job seekers as part of a “recruiting” process. argenx does not request financial information or money from job seekers. Legitimate emails from argenx employees end in “@argenx.com.” Fraudsters disguise themselves by using similar email addresses (e.g., @argenxhr.com, @argenxcareer.com, etc.) or public domains (@gmail.com, @yahoo.com, etc.). They may use photographs and names of real argenx employees for their fake interviews. argenx does not recruit or post positions on RingCentral, Facebook, or Craig’s List. Our formal recruitment process includes interviews with members of argenx’s talent acquisition team and other interviewers that occur in person at our offices, or via Zoom or Teams video calls. Interview processes that involve a formal offer from argenx will include written employment documentation on official argenx letterhead. argenx takes prompt appropriate and responsive action to fraudulent recruiting efforts when we become aware of them. If you believe you have been victimized by an employment application or a fraudulent recruiting scam, you can contact your local law enforcement authority for guidance or the FBI’s Internet Crimes Complaint Center at www.IC3.gov to file a complaint.

Responsibilities

Lead discovery projects in collaboration with biologists to progress programs from hit identification to clinical candidate nomination. Design and optimize molecules while integrating insights from various internal experts and championing innovative technologies.