Senior Scientist, Reagents Sustaining and Applications (P-5010) at 10x Genomics

Pleasanton, California, United States -

Full Time

Start Date

Immediate

Expiry Date

01 Jun, 26

Salary

214400.0

Posted On

03 Mar, 26

Experience

10 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Product Development, Troubleshooting, Molecular Biology, Single Cell Assays, Reagent Manufacturing, Quality Control, Statistical Analyses, Protocol Changes, Process Improvements, qPCR, Nucleic Acid Isolation, Cell Handling, Library Preparation, Bioanalyzer, JMP, R

Industry

Biotechnology Research

Description

We are seeking a Senior Scientist to join the Reagent Sustaining and Applications group to lead sustaining efforts for our Chromium Single Cell products. The role interfaces with R&D, Production, Marketing, and Support to provide the best products to our customers from pre-launch to end of life. The ideal candidate should have deep expertise in product development, troubleshooting complex issues, and understanding of molecular biology, including single cell assays, reagent manufacturing, and developing assays for quality control or manufacturing environments. What you will be doing: Lead efforts in testing new materials, tools, and workflows to improve 10x’s state-of-the-art products. Collaborate with key internal and external partners to troubleshoot and mitigate any issues that may arise in 10x’s Chromium product line. Design and execute experiments to assess the impact of protocol, reagent, or process changes on 10x’s Assays. Design, test, and implement process improvements in 10x’s Chromium product line. Perform statistical analyses on key assay and QC metrics. Update manufacturing documents and present results. Minimum Requirements: BS, MS or PhD in molecular biology, biochemistry, genetics, microbiology, analytical chemistry, or related fields. 12+ years (BS), 10+ years (MS) or 5+ years (PhD) of relevant experience in reagent or assay development and optimization, preferably in the Biotechnology industry. Experience analyzing large-scale single-cell or spatial transcriptomics datasets to derive biologically meaningful insights and/or diagnostic biomarkers. Ability to design and execute experiments to measure the impact of process improvements and/or formulation changes. Experience with a broad variety of molecular biology and analytical techniques including qPCR, nucleic acid isolation, use of plate readers, Bioanalyzers, gel imagers, real-time PCR instruments, etc. Experience with single cell assays including cell handling, library preparation and downstream analysis. Experience investigating, identifying, documenting, communicating, and resolving quality control issues in a controlled manufacturing environment. Experience defining, documenting, communicating, and transferring new manufacturing workflows into controlled manufacturing environments. Meticulous attention to detail and a conscientious work ethic. Preferred Qualifications: Hands-on experience with the 10x Chromium platform. Experience using statistical tools, such as JMP or R to analyze complex data sets, create DOE experiments, and create data trending reports. Experience with bioinformatic analysis of Next Generation Sequencing data from Illumina platforms. Previous experience supervising and/or mentoring junior staff or leading a multifunctional project team. Ability to prioritize competing projects based on impact and alignment with company goals. #LI-ES1 #LI-onsite Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience. At 10x, base pay is also just one component of the Company’s total compensation package. This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company’s total compensation package. Pay Range $158,400—$214,400 USD About 10x Genomics At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience. Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law. 10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

Responsibilities

This role involves leading sustaining efforts for Chromium Single Cell products by testing new materials and collaborating internally and externally to troubleshoot and mitigate issues in the product line. The scientist will design and execute experiments to assess changes and implement process improvements, performing statistical analyses on key metrics and updating manufacturing documents.