Sr. Associate Scientist, Gene Editing Process Development at BristolMyers Squibb
Seattle, Washington, USA -
Full Time


Start Date

Immediate

Expiry Date

09 Nov, 25

Salary

91.0

Posted On

09 Aug, 25

Experience

0 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

No

Skills

Biochemistry, Molecular Biology, Aseptic Technique, Dialysis, Chemical Engineering, Chromatography, Jmp, Experimental Design, Mammalian Cell Culture, Tff, Technical Writing, Bioengineering, Teams, Gene Therapy

Industry

Hospital/Health Care

Description

WORKING WITH US

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .

Key Responsibilities

  • Plan and execute PD studies for optimizing the production of nucleic acids
  • Characterize the functional properties of nucleic acids in genomic editing applications
  • Maintain and process primary human T cells, including thawing, passaging, and cryopreservation.
  • Plan and execute experiments to optimize GERM formulations for non-viral delivery to T cells
  • Organize and maintain GERM inventories, and related quality data, for distribution across the Seattle site
  • Analyze data and effectively communicate experimental results to research scientists and maintain proper documentation of experimental results, including ELN entries and development reports.
  • Assist in identifying GERM pCQA’s from literature and in-house biophysical characterization

Basic Qualifications

  • M.S or B.S. in Biochemistry, Molecular Biology, Bioengineering, Chemical Engineering, or related disciplines
  • 5-8 years of industry experience in process development and/or gene editing-related development
  • Independently motivated with the ability to multitask and work in teams.
  • Desire and drive to learn the biological mechanism of cell and gene therapy products
  • Ability to communicate clearly and concisely through oral presentation and technical writing

Preferred Qualifications

  • Demonstrated ability to use scientific literature and other resources to generate and test hypotheses
  • Previous experience with in vitro mammalian cell culture and proper aseptic technique
  • Background in CRISPR-based technology and/or chemically synthesized RNA oligonucleotides
  • Familiarity with purification processes for in vitro produced nucleic acids (chromatography, TFF, dialysis, etc.)
  • Familiarity with basic analytical assays used for assessing gene editing (e.g., ddPCR, ELISA, CGE, NGS etc.)
  • Experience with statistical analysis and experimental design using JMP

The starting compensation for this job is a range from $91 ,830 - $111,300, plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience.
Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.
If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

How To Apply:

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Responsibilities
  • Plan and execute PD studies for optimizing the production of nucleic acids
  • Characterize the functional properties of nucleic acids in genomic editing applications
  • Maintain and process primary human T cells, including thawing, passaging, and cryopreservation.
  • Plan and execute experiments to optimize GERM formulations for non-viral delivery to T cells
  • Organize and maintain GERM inventories, and related quality data, for distribution across the Seattle site
  • Analyze data and effectively communicate experimental results to research scientists and maintain proper documentation of experimental results, including ELN entries and development reports.
  • Assist in identifying GERM pCQA’s from literature and in-house biophysical characterizatio
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