POSITION OVERVIEW

We are seeking a highly motivated, results-oriented, and collaborative individual to join our Bioinformatics and Analytics team as a Senior/Staff Bioinformatics Production Scientist. In this role, you will combine genomics expertise with strong production engineering skills to design and implement robust, scalable computational pipelines for large-scale NGS data processing and interpretation.
This role is critical in advancing our bioinformatics capabilities to ensure best-in-class performance for Twist Bioscience’s production pipelines. You will be responsible for architecting high-throughput workflows, maintaining reliable bioinformatics infrastructure, and collaborating with Field Application Scientists (FAS) to optimize pipelines that directly support customer needs and field operations.

REQUIRED QUALIFICATIONS

• Education & Experience:
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• Master’s degree with 6–8 years of industry experience, or a Ph.D. with 3+ years of industry experience in Bioinformatics, Computational Biology, Computer Science, or a related field.

• Bioinformatics & Production Pipeline Expertise:
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• Experience designing, implementing, and optimizing production-scale bioinformatics pipelines for NGS data.

• Strong understanding of workflow orchestration frameworks (e.g., Nextflow, Snakemake, Airflow).
• Hands-on experience with large-scale genomic data processing and storage solutions.
• Background in assay development, genomics-based diagnostics, or quality control for high-throughput NGS data.
• Software Development & DevOps Skills:
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• Proficiency in Python.

• Strong familiarity with containerization (Docker, Kubernetes), CI/CD, and cloud platforms (AWS, GCP, or Azure).
• Experience with monitoring, logging, and alerting tools for bioinformatics workflows.
• Cross-Functional Collaboration & Support:
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• Ability to work closely with Field Application Scientists, translating field needs into scalable computational solutions.

• Strong troubleshooting skills and the ability to identify, debug, and resolve pipeline-related challenges in a high-throughput environment.

PREFERRED QUALIFICATIONS

• Experience with Rust, C++, SQL/dbt is a plus
• Strong grasp of infrastructure automation, cloud-native workflows, and scalable computing architectures.
• Familiarity with databases (SQL, dbt) and distributed computing frameworks.
• Experience with high-performance computing (HPC) environments and storage optimization strategies

Please refer the Job description for details