Site: The Brigham and Women’s Hospital, Inc.
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

JOB SUMMARY

Carries out a broad range of technically advanced research activities and procedures; evaluates conclusions and has considerable latitude to modify or devise methods and techniques as necessary to achieve desired results; typically supervises technical and sometimes administrative elements of the research unit. Helps onboard new staff and train them in the lab.

Essential Functions

• Develop or have input into modifications of existing assay techniques, experimental protocols, or new procedures.
• Synthesizes and interprets results.
• Prepares written and/or verbal status reports.
• Performs statistical analysis and makes recommendations.
• Independently performs non-routine, highly specialized experimental procedures.
• Composes and may present sections of research reports and manuscripts.

QUALIFICATIONS

Education
Bachelor’s Degree Related Field of Study required
Can this role accept experience in lieu of a degree?
No

Key Responsibilities

• Design and perform experiments using mouse models and human samples
• Apply genomics, flow cytometry, spatial profiling, and other advanced techniques
• Analyze and interpret data from mouse and human studies
• Harvest, process, and analyze tissues from mouse models
• Prepare genomic sequencing libraries and ensure sample quality
• Manage mouse colonies, genotyping, and maintain detailed records
• Collaborate, troubleshoot, and contribute to scientific publications and presentations
• Be willing to learn new techniques as needed for project development

Experience
Experience in an academic or laboratory research setting 3-5 years required

Knowledge, Skills and Abilities

• Skilled in mouse handling, genotyping, and in vivo experiments
• Experienced with flow cytometry and immune profiling
• Proficient in nucleic acid extraction and library preparation
• Excellent communication skills.
• Good interpersonal skills and the ability to oversee the work of others.
• Ability to work independently.
• Ability to identify problems and develop solutions.
• Ability to prioritize tasks and set deadlines.
• Strong database management and overall computer skills.
• Functions with speed, precision and an understanding of theory behind tests and procedures.

Essential Functions

• Develop or have input into modifications of existing assay techniques, experimental protocols, or new procedures.
• Synthesizes and interprets results.
• Prepares written and/or verbal status reports.
• Performs statistical analysis and makes recommendations.
• Independently performs non-routine, highly specialized experimental procedures.
• Composes and may present sections of research reports and manuscripts

Key Responsibilities

• Design and perform experiments using mouse models and human samples
• Apply genomics, flow cytometry, spatial profiling, and other advanced techniques
• Analyze and interpret data from mouse and human studies
• Harvest, process, and analyze tissues from mouse models
• Prepare genomic sequencing libraries and ensure sample quality
• Manage mouse colonies, genotyping, and maintain detailed records
• Collaborate, troubleshoot, and contribute to scientific publications and presentations
• Be willing to learn new techniques as needed for project developmen