Sr. Research Associate, Oligonucleotide Chemistry at EMD Serono Research & Development Institute

Billerica, Massachusetts, United States -

Full Time

Start Date

Immediate

Expiry Date

08 Aug, 26

Salary

124800.0

Posted On

10 May, 26

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Oligonucleotide Synthesis, HPLC, HPLC-MS, Deprotection, Purification, Desalting, Lyophilization, Anion-Exchange Chromatography, Reverse-Phase HPLC, ASO/siRNA Processing, Laboratory Documentation, Instrument Troubleshooting

Industry

Pharmaceutical Manufacturing

Description

Work Your Magic with us! Start your next chapter and join EMD Serono. Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. Your Role: Synthesis of oligonucleotides, deprotection, purification, desalting and lyophilization of oligonucleotides. Ability to operate Expedite/ABI/Mermade synthesizers and HPLC systems. Prepare oligonucleotide synthesis reagents and synthesize, process, and purify ASO/siRNA using automated instruments by anion-exchange and reverse-phase HPLC systems. Desalt, concentrate, and lyophilize final Oligo’s material using appropriate instrumentation or techniques. Maintain a well-documented laboratory notebook and follow the safe laboratory practices. Operate and troubleshoot available instruments including HPLC and MS. Maintain an electronic laboratory notebook and miscellaneous documentation and maintain reagent inventory. Minimum Qualifications: Bachelor’s Degree in Chemical Engineering, Chemistry, Biochemistry or related Engineering or Life Science discipline. 2+ years of Oligonucleotide chemistry OR Master’s Degree Chemical Engineering, Chemistry, Biochemistry or related Engineering or Life Science discipline. Preferred Qualifications: Good understanding of Oligonucleotide chemistry. Experience with a wide range of Oligo purification/analytical techniques, especially HPLC and/or HPLC-MS. Experience in performing desalting by using gel filtration or membrane filtration techniques. High degrees of flexibility and motivation in a fast-paced work environment. Pay Range for this position: $81,120 $124,800. The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here. What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress! Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

Responsibilities

The role involves the synthesis, purification, and processing of oligonucleotides using automated instruments and HPLC systems. Responsibilities include maintaining detailed laboratory notebooks and managing reagent inventories.