Sr. Scientist II, Brain Transport Biology

Cambridge, MA

• Function: Research & Development
• Job Type: Full-time

Job ID: R00131858
Company Description
AbbVie’s mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio.
Job Description
The Discovery Neuroscience In Vivo Pharmacology group in Cambridge, Massachusetts, is seeking a highly skilled and self-motivated scientist to join a dynamic team supporting target identification, validation, and drug transport facilitation over brain barriers. The ideal candidate will also have people and project management experience and has experience making tangible contributions to the discovery pipeline.

MINIMUM QUALIFICATIONS:

• Bachelor’s Degree or equivalent education and typically, 12 years of experience, Master’s Degree or equivalent education and typically 10 years of experience, PhD and typically 4 years of experience.
• Background in receptor and / or transporter biology
• Background in brain barriers biology
• Proven track record of working in multidisciplinary in vivo pharmacology teams
• Experience with in vivo models of neurodegeneration, particularly with models of Alzheimer’s and Parkinson’s Disease
• Proven track record in characterizing complex biotherapeutics in vivo (biologics, small molecules, siRNA)
• Experience managing direct reports, including providing performance evaluations and development opportunities
• Excellent organizational skills and the ability to manage multiple projects simultaneously
• Demonstrated ability to collaborate effectively in a dynamic, cross-functional matrix environment
• Candidate must be a goal-oriented team player with excellent verbal and written communication skills and strong “can-do” attitude

PREFERRED QUALIFICATIONS:

• Prior project and team leadership in the pharmaceutical / biotech industry
• Experience in managing external collaborations
• Experience with ex vivo readouts including immunohistochemistry and biochemistry (ELISA, WB)
• Experience with image analysis
  Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.
• This job is eligible to participate in our long-term incentive programs

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company’s sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
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• Responsible for design and implementation of in vivo testing of multispecific biologics, small molecules, and siRNAs to support projects in the areas of Alzheimer’s and Parkinson’s disease
• Serve as an in vivo representative in cross-functional teams with Discovery Biotherapeutics, DMPK, and Development Sciences colleagues, providing project updates, analysis, and strategic advice
• Collaborate with colleagues at various AbbVie and external sites
• Serve as the project lead responsible for coordinating activities and transitions from Hit Generation through Candidate Nomination
• Identify and solve technical problems independently, implement new assays and workflows, conceive and implement innovative research ideas
• Supervise junior scientists providing scientific and technical leadership in the design and execution of in vivo and ex vivo efficacy assessments, and be accountable for the effective performance of the team
• Ensure consistency and quality of technical reports
• Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents
  Qualifications