Stem Cell Biologist at Eurofins

Cambridge, Massachusetts, United States -

Full Time

Start Date

Immediate

Expiry Date

04 Jan, 26

Salary

135000.0

Posted On

06 Oct, 25

Experience

5 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Stem Cell Biology, iPSC Culture, CRISPR, Immunology, Drug Discovery, Assay Development, Data Analysis, Collaboration, Documentation, Communication, Functional Validation, Organoid Models, Biochemical Assays, Research Environment, Target Validation, Cell Differentiation

Industry

Medical and Diagnostic Laboratories

Description

Company Description Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products. In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products. Job Description Eurofins PSS is seeking a passionate and dedicated experimental stem cell biologist. The candidate will work directly on the client site in Cambridge, MA, and will collaborate with scientists from multiple therapeutic areas (Immunology and Neuroscience) to validate targets, drug candidates, and biomarkers with the objective of developing improved human model systems and leveraging these translational model systems to better understand the mechanism of action for early discovery targets. The candidate will utilize genetic (CRISPR) and pharmacological manipulations of induced pluripotent stem cell (iPSC) model systems to validate the role of targets in mechanisms related to the pathobiology of human diseases. The focus of the role will be to differentiate iPS-derived immune cell types for use in cell-based assays and to incorporate them into intestine and skin organoid model systems for the client Immunology team. The candidate will support the client’s dynamic and innovative early discovery research environment and will be expected to work both independently and collaboratively with colleagues. This is a hands-on position. The ideal candidate shall have excellent lab skills, strong documentation skills, the ability to analyze and summarize data to draw conclusions, and make recommendations. Key responsibilities include, but are not limited to: Formulate and execute assay protocols to differentiate iPSC lines into immune cell types, including but not limited to Mast, dendritic, macrophage, and T-cells. To develop methods for QC and functional validation of immune cell types in collaboration with experimental scientists within different client groups. To incorporate immune cell types into organoid models in collaboration with experimental scientists within the client environment. Work with cross-functional teams, including disease area biologists, pharmacologists, and chemist,s to develop and implement functional assay readouts to validate Immunology drug targets using iPSC-derived model systems. Effectively communicate and present data to a diverse group of scientist,s including senior managers. Qualifications Required: Candidate with PhD with 4+ years of experience in stem cell biology or related biological fields. Possess excellent communication skills with ability to present clear scientific data and project updates to a diverse group of scientists. Experience working in collaborative research environments to advance scientific projects. Preferred: Experience with human stem cell culture, culturing iPSCs, executing differentiation protocols with iPSCs to produce terminal cell types, genetic/genomic manipulations (CRISPR), and biochemical assays are needed. Previous experience working on drug discovery projects. Experience in the field of Immunology Additional Information Position is full-time, Monday - Friday, 8:00 am - 5:00 pm. Candidates currently living within a commutable distance of Cambridge, MA, are encouraged to apply. Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options Life and disability insurance 401(k) with company match Paid vacation and holidays Compensation is between 130,000-135,000 depending on education and experience Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

Responsibilities

The candidate will formulate and execute assay protocols to differentiate iPSC lines into immune cell types and develop methods for QC and functional validation of these cell types. They will work with cross-functional teams to validate Immunology drug targets using iPSC-derived model systems.