Summer Co-op/Modeling at GSK

Upper Providence, Pennsylvania, United States -

Full Time

Start Date

Immediate

Expiry Date

03 Jun, 26

Salary

43.0

Posted On

05 Mar, 26

Experience

0 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

PBPK Modeling, DMPK, In Vitro, Pre-clinical, Clinical, Compartmental Pharmacokinetics, Physiologically Based Pharmacokinetics, Pharmacodynamics, Model Validation, Human Dose Predictions, Drug-Drug Interactions, Small Molecules, Large Molecules, Scientific Writing, Verbal Communication, Presentation

Industry

Pharmaceutical Manufacturing

Description

Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. Department Description Drug Metabolism & Pharmacokinetics (DMPK) Group is responsible for integrating the absorption, distribution, metabolism, and elimination (ADME) characteristics of drug candidate molecules from in vitro, pre-clinical and clinical information. More specifically DMPK Modeling group provides in vitro to in vivo translation, human dose predictions, and clinical using compartmental pharmacokinetics (PK) and physiologically based pharmacokinetics (PBPK) and pharmacodynamics (PD). Watch this before you apply! GSK Early Careers Top Tips: Learn practical advice from GSK on how to prepare a standout application and succeed in your early careers journey: GSK Early Careers Top Tips Job Description This position will allow the selected candidate to develop their PBPK modeling skills within in the DMPK modeling group. The PBPK scientist will have the opportunity to learn about PBPK applications from early discovery to late-stage drug development for small and large molecules alike. Along with other DMPK team members, this scientist will collaborate across various cross-functional teams such as toxicology, biology, chemistry, clinical pharmacology, and formulations and will contribute to the application of model informed drug development strategies. Responsibilities to include (but not limited to): Independently build and validate PBPK models to support various applications including and not limited to human dose predictions, drug-drug interactions, dosing routes (e.g. Long acting injectables etc.) for small/large molecules and/or new modalities. Present modelling outputs in internal team and/or department meetings as well as the opportunity to publish any completed work. Minimum Qualifications Pursuing a Master's or PhD degree in a relevant scientific discipline (Math, Pharmacology, Biochemistry or other DMPK related sciences). Must be able to work full-time (35-40 hours/week) throughout the duration of the 6-month co-op (June ~ December 2026). Must have an active student status and/or within 12 months post-graduation from a BS or MS degree program. Post-doctoral candidates are not eligible. Preferred Qualifications Experience with application of PBPK software SimCYP. Basic knowledge of DMPK processes in drug discovery and development. Basic understanding of the in vitro/ in vivo experiments used to describe general ADME principles especially drug absorption and drug distribution. Scientific writing and presentation ability with excellent verbal communication skills. Eligibility Requirements Must successfully pass a drug screen and background check prior to assignment target start date. Once your application is submitted, you will be prompted to complete our immersive GSK Digital Assessment. A passing score is required to proceed in the application process. After completing the assessment, a recruiter will review your application and contact you with next steps. Please note: If you do not receive an automated email after submitting your application, be sure to check your spam folder. Benefits While GSK embraces a flexible work environment, we do require certain positions to be onsite. Candidates who are hired for an on-site role or hybrid role, and reside outside of 50-miles from their assigned work location, are eligible for relocation stipend. This is a one-time payment to help offset housing & relocation expenses. Please refer to the position details for the requirements of each position. GSK Interns and Co-ops are offered a competitive hourly pay rate and benefits. Please note, benefits eligibility determined the month following date of hire. This job posting is for a temporary role as an employee of Atrium on assignment at GSK. The individual selected for this role will be offered the role as an employee of Atrium; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by Atrium upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on several factors, including skills, competencies, experience, educational degree obtained, location and/or being pursued and other job-related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirement. Pay Rate Range: $22/hr to $43/hr Interested in learning more? Register now on our digital learning platform (GSK Get Ahead - Connectr) where you can access interview and assessment hints and tips, speak to a mentor and learn more about life at GSK.

Responsibilities

The selected candidate will develop PBPK modeling skills within the DMPK modeling group, learning applications from early discovery to late-stage development for various molecules. Responsibilities include independently building and validating PBPK models for applications like human dose predictions and drug-drug interactions, and presenting modeling outputs.