Summer Intern/ViiV Translational Research & HIV Cure at GSK

Durham, North Carolina, United States -

Full Time

Start Date

Immediate

Expiry Date

31 Jul, 26

Salary

40.0

Posted On

02 May, 26

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Lipid nanoparticle formulation, Flow cytometry, Cell culture, Molecular weight cut-off filtration, Dynamic light scattering, RNA quantification, Aseptic technique, PBMC isolation, T cell culture, Data analysis, Electronic lab notebook documentation, Immunology, Virology, Nanomedicine, Spectrometry

Industry

Pharmaceutical Manufacturing

Description

Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. Department Description ViiV Healthcare is a global specialty HIV company, the only one that is 100% focused on researching and delivering new medicines for people living with, and at risk of, HIV. Born out of a partnership between GSK and Pfizer in 2009, with Shionogi joining in 2012, at ViiV Healthcare we are determined to help end the HIV epidemic. Within the Translational Research and Cure lab, we focus on advancing novel treatments to benefit people affected by HIV. Watch this before you apply! GSK Early Careers Top Tips: Learn practical advice from GSK on how to prepare a standout application and succeed in your early careers journey: GSK Early Careers Top Tips Job Description The Translational Research and HIV Cure team within ViiV Healthcare is looking for a summer intern to test various lipid nanoparticle (LNP) formulations in a pre-defined suite of assays. The primary goal of this work is to generate novel LNP formulations and determine transfectional efficiency as well as specific cellular uptake of LNPs in primary cell cultures. All assays will be run and analysis performed in accordance with established protocols. The selected candidate’s responsibilities will include, but not limited to: Purify and concentrate preparatory lots of lipid nanoparticle (LNP) formulations using molecular weight cut-off (MWCO) and dead-end filtration. Characterize the concentrated LNP preparations using dynamic light scattering (DLS) and RNA quantification assays. Distribute and label LNP preps into single use aliquots. Treat PBMC and isolated T cell cultures with LNP preps using 96-well plate format. Run treated cultures on flow cytometry assays to determine LNP transfectional efficiency and select uptake in different cellular populations. Analyze resultant data and carefully document experimental methods and findings in electronic lab notebooks or forms associated with assay protocols. Attend team meetings and present results to the broader research team. Minimum Qualifications Pursuing a PhD or MS in Immunology, Virology, Nanomedicine/Nanotechnology, or a related field. Minimum of 3 years of laboratory experience in immunology, virology, nanomedicine, or a related field. Must be able to work full-time (35-40 hours/week) throughout the duration of the 12-week internship (May/June-August 2026). Must have an active student status and/or within 12 months post-graduation from a MS degree program. Post-doctoral candidates are not eligible. Preferred Qualifications Experience working with human blood and other donor specimens. Experience formulating and purifying compounds and LNPs from stock solutions using dead-end and molecular weight cut-off filtration. Experience testing samples in cuvette based DLS or spectrometry assays; Work with conducting zeta potential assays on a Malvern Zetasizer instrument preferred. Quantifying nucleic acid concentration using dye-based spectrometry assays. Experience working with human blood and other donor specimens. Experience isolating and culturing primary PBMCs and T cells using aseptic technique in a biosafety cabinet. Ability to run compound and LNP treatment assays on primary cells in 96-well format. Experience with running and analyzing data from 8 color flow cytometry assays. Documentation of assay results in electronic notebook entries or in report forms associated with the assay protocols. Eligibility Requirements Must successfully pass a drug screen and background check prior to assignment target start date. Once your application is submitted, you will be prompted to complete our immersive GSK Digital Assessment. A passing score is required to proceed in the application process. After completing the assessment, a recruiter will review your application and contact you with next steps. Please note: We recommend using your personal email when submitting your application as school emails tend to block external senders. If you do not receive an automated email after submitting your application, be sure to check your spam folder. Benefits While GSK embraces a flexible work environment, we do require certain positions to be onsite. Candidates who are hired for an on-site role or hybrid role, and reside outside of 50-miles from their assigned work location, are eligible for relocation stipend. This is a one-time payment to help offset housing & relocation expenses. Please refer to the position details for the requirements of each position. GSK Interns and Co-ops are offered a competitive hourly pay rate and benefits. Please note, benefits eligibility determined the month following date of hire. This job posting is for a temporary role as an employee of Atrium on assignment at GSK. The individual selected for this role will be offered the role as an employee of Atrium; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by Atrium upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on several factors, including skills, competencies, experience, educational degree obtained, location and/or being pursued and other job-related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirement. Pay Rate Range: $21/hr to $40/hr Interested in learning more? Register now on our digital learning platform (GSK Get Ahead - Connectr) where you can access interview and assessment hints and tips, speak to a mentor and learn more about life at GSK.

Responsibilities

The intern will generate and test lipid nanoparticle (LNP) formulations using various assays to determine transfectional efficiency and cellular uptake. Responsibilities include purifying preparations, characterizing samples, treating primary cell cultures, and documenting experimental findings.