Summer Research Intern - Platform Technology (Undergraduate level) at Septerna

South San Francisco, California, United States -

Full Time

Start Date

Immediate

Expiry Date

28 Apr, 26

Salary

25.0

Posted On

28 Jan, 26

Experience

0 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Biochemical Assays, Biophysical Assays, Data Analysis, Experimental Data, Problem Solving, Collaboration, Communication, Organizational Skills, Quantitative Skills, Scientific Literature, Project Management, Assay Development, Thermal Shift Methods, Surface-Based Binding Assays, Plate-Based Workflows, Python, R

Industry

Biotechnology

Description

Septerna is a biotechnology company based in South San Francisco, CA on a mission to develop life-changing medicines for patients with the vision to become the industry-leading G protein-coupled receptor (GPCR)-focused drug discovery company. The company’s Native Complex Platform™ recapitulates GPCRs with their native structure, function, and dynamics outside of the cellular context. This approach enables novel access to modern structural and screening technologies used in industrial-scale drug discovery for the entire class of GPCRs. Septerna has an emerging pipeline of GPCR-targeted small molecule programs with potential for growth to target many GPCRs that have been undruggable and unexploited to date. We are excited to expand our multidisciplinary team of individuals focused on creating revolutionary medicines to address the unmet needs of patients. At Septerna we strive to embrace diversity of thought, expertise, and background through collaboration. To join our ambitious team, be prepared to bring your real self to work every day; grow and learn from a talented team of drug hunters, scientists, and business professionals; and contribute your passion, creativity, and energy to accomplish our mission. We share a fearless pursuit of ground-breaking innovations and cultivate an environment where our employees succeed by learning from each other and working as a team. We are committed to the development of meaningful therapeutics for patients with indications of high unmet need. This is a tremendous opportunity to work with talented individuals on the frontlines of therapeutic discovery and development. You will directly help move therapies through preclinical research, positioning them for success in the clinic. The successful candidate will add their passion, unique talents, and expertise to a dynamic team motivated to discover new disease-modifying therapeutics for patients in a fast-paced environment. For more information see: www.septerna.com. About The Role The Summer Research Intern, Platform Technology will join the Biophysics team and support the development and application of biophysical assays to advance our platform technologies. This intern will work closely with scientists across functions to generate, analyze, and interpret experimental data in a collaborative lab environment. The role offers hands-on research experience and exposure to cutting-edge drug discovery technologies in a fast-paced biotech setting. Each Intern will be assigned to a single function with a specific project for the 3-month Internship term. Opportunity Participate in weekly project team meetings. Provide a final presentation of project work to senior leaders. Qualifications Pursuing a Bachelors (enrolled student) in organic chemistry, medicinal chemistry, chemical biology, biochemistry or related field. Ability to interpret and analyze experimental data, troubleshoot experiments, and propose solutions to research challenges. Excellent communication, collaboration, and interpersonal skills Self-motivated, with the ability to work both independently and collaboratively Ability to read and digest scientific literature Strong organizational, problem solving, analytical and quantitative skills Ability to efficiently manage short timelines Authorized to work in the U.S. i.e. (applicants who require employer sponsored visas now or in the future are not eligible to apply) Must be at least 18 years old Ability to complete 12 consecutive weeks between May and September on-site in South San Francisco. Enrolled currently in graduate degree at an accredited college/university and returning to the University/and or College following the internship Strict adherence to lab safety rules and regulations Preferred Qualifications Excellent communication, collaboration, and interpersonal skills. Ability to work both independently and collaboratively. Ability to read and digest scientific literature. Strong organizational, project management, problem solving, analytical and quantitative skills. Ability to efficiently manage short timelines Ability to keep and maintain records and experiments within an electronic lab notebook Prior laboratory experience in biochemical or biophysical assays, with exposure to assay development and optimization is highly desired and may include but is not limited to: Familiarity with thermal shift–based methods (DSF, nanoDSF) and/or surface-based binding assays (SPR, BLI) Experience analyzing experimental data from equilibrium and kinetic assays Experience with plate-based workflows, liquid handling, and data acquisition platforms Experience with common scientific data and documentation tools (e.g., GraphPad Prism, Excel, Benchling, PowerPoint) Experience with scientific scripting or data analysis in Python or R is a plus, particularly for automation of data analysis and visualization of large plate-based datasets Interest in working on technically complex projects with cross-program impact Relocation benefits are not available for this job posting. The expected salary range for this position based on the primary location of South San Francisco, CA is $25.00 per hour depending of undergraduate/graduate level and year. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits. Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited. We are an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. Septerna participates in the E-Verify program. California Consumer Privacy Act Privacy Notice For Job Applicants. If you are a California resident, click here for our CCPA Notice.

Responsibilities

The Summer Research Intern will support the development and application of biophysical assays to advance platform technologies. They will work closely with scientists to generate, analyze, and interpret experimental data in a collaborative lab environment.