Synthetic DNA Process Development Scientist at Eurofins

Louisville, Kentucky, United States -

Full Time

Start Date

Immediate

Expiry Date

24 Jul, 26

Salary

0.0

Posted On

25 Apr, 26

Experience

5 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Oligonucleotide synthesis, Purification process development, Organic chemistry, HPLC, LC-MS, Process scale-up, Ion-exchange chromatography, Desalting, SOP development, Technical reporting, GMP compliance, Automated DNA/RNA synthesizers, Modified nucleotides, High-throughput production, Analytical chemistry, Troubleshooting

Industry

Medical and Diagnostic Laboratories

Description

Company Description Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. Eurofins is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. The Group also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products. In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to 55,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 50 countries. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products. Job Description Position Summary We are seeking a highly skilled and motivated Organic Chemist with expertise in oligonucleotide synthesis and purification to support process development and manufacturing. This role focuses on developing, optimizing, and scaling chemical processes for high-throughput and high-quality oligonucleotide production. Key Responsibilities • Design, develop, and optimize chemical synthesis processes for nucleotides and oligonucleotides • Process development and scale-up from R&D to manufacturing • Develop and improve oligonucleotide purification processes (e.g., HPLC, ion-exchange, desalting) • Troubleshoot synthesis and purification challenges to improve yield and purity • Collaborate with manufacturing, QC, and engineering for process transfer • Evaluate new chemistries and technologies • Author SOPs, batch records, and technical reports • Ensure compliance with quality systems • Mentor lab technicians Qualifications • Ph.D. or Master’s degree in Organic Chemistry or related field (required) • Minimum 5 years of industrial experience in chemical synthesis • Experience with solid-phase oligonucleotide synthesis • Experience in oligonucleotide purification process development • Strong analytical skills (HPLC, LC-MS) • Experience scaling processes to manufacturing Preferred Qualifications • Experience in GMP or regulated environments • Familiarity with automated DNA/RNA synthesizers • Knowledge of modified nucleotides • Experience in high-throughput oligo production Work Environment • Fast-paced, collaborative environment • Ability to manage multiple priorities • Occasional off-hours support as needed Additional Information Schedule: Monday-Friday 8:00am-5:00pm Weekend Work as needed What we offer: Excellent full time benefits including comprehensive medical coverage, dental, and vision options Life and disability insurance 401(k) with company match Paid vacation and holidays Eurofins USA Clinical Diagnostics is a Disabled and Veteran Equal Employment Opportunity employer.

Responsibilities

The scientist will design, develop, and optimize chemical synthesis and purification processes for oligonucleotides to support manufacturing. They will also collaborate with cross-functional teams to ensure process transfer, compliance with quality systems, and technical documentation.