Technician CLD at Celonic AG

Basel, Basel-City, Switzerland -

Full Time

Start Date

Immediate

Expiry Date

27 Aug, 26

Salary

0.0

Posted On

29 May, 26

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Cell Line Development, Gene Synthesis, Vector Cloning, Plasmid Purification, Transfection Techniques, Clone Selection, Clonality Assessment, Small-scale Bioreactors, E.coli Culture, CHO Cell Suspension, Flow Cytometry, Molecular Biology, SOP Writing, Cell Banking, qPCR, ELISA

Industry

Pharmaceutical Manufacturing

Description

The Position The Technician CLD supports the development of processes and/or the analysis for the manufacturing of recombinant proteins with CHO cultures by executing experiments, preparing materials, and collecting data. Your Responsibilities Conduct experiments and applies standard laboratory practices under moderate guidance and supervision within scope and timelines Document executed work in accordance to internal guidelines Support troubleshooting activities in collaboration with Subject Matter Expert Document batch results with a critical mind Write protocols, SOPs, using available templates Drive simple initiatives (in relation to job duties) with limited guidance and supervision within his/her team/group Support technology transfer activities if needed Follows all EHS procedures and laboratory safety standards, maintains a clean and safe workspace, and promptly reports any unsafe conditions, incidents, or near misses Job Requirements Cell Line Development (CLD) technical skills: Gene synthesis, vector cloning, plasmid purification, sequencing, agarose gel electrophoresis Pasmid design software (e.g., vector mapping and annotation tools) Transfection techniques and clone selection workflows; Clonality assessment (e.g. FACSAria, FACSLyric, Single cell printing (VIPS), Cellmetric) Expansion and cryopreservation of cell lines Small-scale bioreactor systems used in early screening (e.g., Ambr15, Breez) E.coli culture, CHO cell suspension Other desirable technical skills: Cell culture expansion in shake flasks, wave bags, and benchtop bioreactors, use of single-use bioreactors at laboratory and pilot scale, Monitoring and control of critical culture parameters (e.g., pH, DO, temperature, agitation, feeding), Routine sampling for cell growth and metabolic profiling, Basic troubleshooting and maintenance of bioreactor and support systems Excellent communication skills (English required, German is a plus) Solution-oriented mindset Ability to work in a fast paced environment Collaborative team player Ability to deal with changes and quickly adjust to new situations Why Celonic? Make a difference by directly impacting patients lives Biologics is an attractive, high growth sector with professional development Offers a multinational and diverse workplace Proud to be a pioneer in “Next Generation” manufacturing technologies Family owned: Entrepreneurial, and short communication lines Basel is a great place to live, play and work in the center of Europe Contact information About us Celonic is a “Pure Play” Biologics Contract Development Manufacturing Organization (CDMO). Celonic’s mission is to help its customers, primarily small to large Biotech Companies, bring life-saving and improving drugs effectively to the market using innovative, “next generation” bioprocessing technologies such as, process intensification and full-perfusion. Celonic has a state-of-the-art Development and Innovation Center in Basel, Switzerland (headquarters), and clinical and commercial GMP manufacturing facilities in Heidelberg, Germany. At present, more than 500 highly qualified employees work at Celonic. Due to the expansion of the company, Celonic is looking for committed and qualified employees. Our job is to make a difference! http://www.celonic.com/

Responsibilities

The Technician CLD supports the manufacturing of recombinant proteins by executing experiments, preparing materials, and collecting data. Responsibilities include documenting batch results, writing protocols and SOPs, and supporting technology transfer activities.