UNIV - Postdoctoral Fellows - Pediatrics: DCRI-1

at  MUSC

JOB DESCRIPTION SUMMARY

The Laboratory of Molecular Neurodegeneration and Neurotherapeutics in the Darby Children’s Research Institute at the Medical University of South Carolina at Charleston is recruiting two highly motivated and skilled postdoctoral fellows to investigate the pathogenesis of age-related and childhood neurodegenerative diseases using cellular and rodent disease models. The laboratory adopts a translational approach to identify and validate novel therapeutic strategies.

JOB DESCRIPTION

The Laboratory of Molecular Neurodegeneration and Neurotherapeutics in the Darby Children’s Research Institute at the Medical University of South Carolina at Charleston is recruiting two highly motivated and skilled postdoctoral fellows to investigate the pathogenesis of age-related and childhood neurodegenerative diseases using cellular and rodent disease models. The laboratory adopts a translational approach to identify and validate novel therapeutic strategies. To achieve these goals, the laboratory uses a multidisciplinary approach employing molecular, cellular, and biochemical experimental techniques in several model systems, including human cell lines, primary neuronal cultures, genetically modified mouse models, and human brain tissue. The successful candidates are expected to lead the projects independently and manage transgenic mouse colonies and cellular models to address significant questions regarding the emergence of age-related and childhood neurodegenerative diseases, discover disease-relevant biomarkers, and develop novel therapeutic approaches. The applicants must have a demonstrated track record, including first-author papers in biological sciences/neurosciences or related fields of study. The ability to collaborate in a team and multi-lab environment is a must. Experience in transcriptomics, molecular biology, biochemical assays, and handling of genetically engineered mouse and rat models is desired. Salary will be based on experience per NIH scale. Interested candidates should send their CVs and contact information of three references to Dr. Bobby Thomas (thomasbo@musc.edu).
Educational requirements:
Doctorate in a related field of study.
Job Duties:
35% Lead the projects independently and manage transgenic mouse colonies and cellular models to address significant questions regarding the emergence of age-related and childhood neurodegenerative diseases, discover novel disease-relevant biomarkers, and develop novel therapeutic approaches.
35 % Use a multidisciplinary approach utilizing molecular, cellular, and biochemical experimental techniques in several model systems, including human cell lines, primary neuronal cultures, genetically modified mouse models, and human brain tissue.
30% In collaboration with the PI, write papers in biological sciences/neurosciences or related fields of study.

ADDITIONAL JOB DESCRIPTION

Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform ‘pinching’ operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
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Please refer the Job description for details