Vice President, Global Supply & Operations at ADC Therapeutics America Inc

New Providence, New Jersey, United States -

Full Time

Start Date

Immediate

Expiry Date

30 Jan, 26

Salary

0.0

Posted On

01 Nov, 25

Experience

10 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

GMP Operations, Supply Chain Management, Technical Operations, Team Leadership, Change Management, External Manufacturing, Regulatory Filings, Operational Excellence, Lean Practices, Budget Management, Procurement, Quality Assurance, Collaboration, Strategic Procurement, Cost Optimization, Continuous Improvement

Industry

Description

Description Transforming Cancer Therapy Together At ADC Therapeutics, we are passionate about revolutionizing cancer treatment. When you join our team, you become part of a mission-driven group of talented individuals dedicated to making a difference in patients' lives. Why ADC Therapeutics ADC Therapeutics (NYSE): is a commercial, global leader and pioneer in the field of antibody-drug conjugates (ADCs) with specialized capabilities from clinical through commercialization. Our CD-19-directed ADC for relapsed/refractory non-Hodgkin lymphoma, ZYNLONTA® (loncastuxamab tesirine lpyl) has received accelerated approval in the United States and conditional approval from the European Commission. ZYNLONTA is also being evaluated in combination with other anti-cancer therapeutics and in earlier lines of therapy as well as other indolent lymphomas to determine if it has potential to treat an even broader range of patients. In addition to ZYNLONTA, ADC Therapeutics has a PSMA-targeting ADC in ongoing development. We are a team of approximately 200 patient-focused, purpose-driven employees with a shared mission to transform the treatment paradigm for patients. If you’re interested in making a difference in the lives of patients worldwide with a team of like-minded colleagues, operating in a flexible work environment, come join us on our journey! To learn more about ADC Therapeutics, our values, and our exceptional culture, please visit us at https://adctherapeutics.com/ and LinkedIn. Position Summary: Reporting to the Chief Technical Officer, as a member of the Technical Operations leadership team, this role will be critical in setting the strategy and realizing the vision for the growth and expansion of ADC Therapeutics' global commercial and clinical supply. The incumbent will lead and mentor an experienced team of manufacturing, technical and supply chain professionals responsible for managing all activities related to supply of ADCT's antibody drug conjugate therapies, including chemistry, cell culture, conjugation, form/fill, label/pack, shipping and logistics. In addition, this role will be responsible for leading efforts to optimize the internal and external networks and business processes to support significant anticipated growth in supply, in collaboration with key Tech Ops leaders. In this role, the incumbent will have overall responsibility for External Partnerships and Network Management, Procurement/ Contracting and Cost Optimization, Supply Chain and Manufacturing Operations, while ensuring all GMP Supply activities are done with a high focus on Quality and Compliance. The preferred location for this position is to be hybrid from the ADCT New Jersey office, but will also consider remote within the US if able to travel to the NJ office and other business locations when needed. What You’ll Do: Lead global supply operations, which includes the manufacturing supply organizations for clinical and commercial supply, external manufacturing, supply chain and partner management Coach, mentor, and develop your team to achieve a high performance, quality and safety focused biotech GMP manufacturing culture, leading the strategic effort to grow our capabilities Global overall accountability for the strategic supply relationships with ADCT's global commercial partners, working closely with Alliance Management to develop and implement more integrated external collaborations to ensure uninterrupted supply to all global markets as new markets launch and expanded indications and combination therapies are pursued. This position will also have overall responsibility for ADCT's global network of CMDOs, collaborating closely with key leaders within Tech Ops to increase the volume and velocity in our supply network by developing and implementing an improved internal and external framework for partnering more effectively with our CMOs, driving lead time and cost reduction while ensuring uninterrupted supply during a period of anticipated growth. In close partnership with Quality, lead the Supply organization to ensure routine supply and continuous improvement, including Lean practices, investigations and change controls, support of external manufacturing and vendor management. Collaborate with Quality to foster a clear and inherent culture of Quality First and Right First Time that ensures high transparency and collaboration between Quality, Operations and our external partners such that we work daily as one team in service of bringing ADCT’s transformative therapeutics to patients, ensuring high quality, responsiveness and value. This role will also have primary budget and procurement responsibility for the Supply Organization, partnering with Finance to drive cost savings, contract optimization and standardization across ADCT's network. In collaboration with Regulatory, author regulatory and technical documents for regulatory submissions in support of manufacturing and serve as subject matter expert in regulatory interactions. Other duties as assigned Requirements Who You Are: BS or BSE in engineering, science, or other relevant discipline plus 20 years of relevant pharmaceutical/biotech experience, or advanced degree plus 15 years of experience. Proven record of accomplishment in GMP pharmaceutical or biotech operations, supply chain and/or technical operations; strong preference for candidates with both biologics and chemistry based experience. Strong team leadership, strategy development / implementation, and change management experience, leading operational teams for routine pharma/biotech market supply in either internal or external manufacturing setting; Experienced external-facing technical leader with track record of high-level performance in managing delivery and relationships with multiple interdependent CDMO partners, and multiple downstream commercial customers (internal and external). Diverse manufacturing supply background in the pharmaceutical / biotech environment, particularly in External Manufacturing management, Supply Chain, internal and external S&OP, MRP, strategic procurement (including but not limited to supply agreement negotiation). Experience with regulatory filings, change control, management of change, regulatory agency audit, partner audits. Proven success in delivering business results with visual management / operational excellence / lean / six sigma, etc A growth mindset and passion for building something new with a talented team, in service of bringing breakthrough medications to patients. Available for domestic and international travel (estimated up to 25% of time, primarily in the US and Europe, possibly Asia). ADC Therapeutics is an equal opportunity employer and will consider qualified applicants for employment. We are committed to building collaborative, engaged teams and fostering a professional and respectful work environment where employees are empowered for success.

Responsibilities

Lead global supply operations and manage all activities related to the supply of ADC Therapeutics' therapies. Optimize internal and external networks to support anticipated growth in supply while ensuring quality and compliance.