Vice President, Pharmaceutical Sciences at Tango Therapeutics

Boston, Massachusetts, United States -

Full Time

Start Date

Immediate

Expiry Date

08 Mar, 26

Salary

408000.0

Posted On

09 Dec, 25

Experience

10 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Clinical Pharmacology, Drug Metabolism, Pharmacokinetics, Preclinical Safety, Drug Discovery, Drug Development, NDA Submission, GLP, GCP, ICH Requirements, Modeling, Simulation, Oncology, Translational Science, Health Authority Interactions

Industry

Biotechnology Research

Description

Company Overview Tango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer. Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer. This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing. The Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts Summary Tango has an exciting new opportunity to join our team as VP, Pharmaceutical Sciences. Reporting to our President of R&D, you will be responsible for Drug Metabolism and Pharmacokinetics, Preclinical Safety and Clinical Pharmacology. You will collaborate with colleagues in drug discovery and drug development to deliver successful IND and NDA submissions. Your Role: You will be a recognized expert in clinical pharmacology with a track record of success in research and development Lead overall scientific, technical, and operational aspects of Pharmaceutical Science for R&D Recruit, develop and mentor talent as you build Pharmaceutical Sciences Collaborate with preclinical and clinical development teams to optimize study design and execution Represent Pharmaceutical Science as subject matter expert on R&D teams and governance boards Establish and maintain productive relationships with key internal business partners, consultants, and CROs What You Bring: PhD or PharmD in clinical pharmacology, pharmacometrics, or related discipline with at least 15 years’ experience in the pharmaceutical and/or biotech industry Experience with small molecule drug development in oncology In-depth knowledge of drug metabolism, pharmacokinetics, biopharmaceutics, drug-drug interactions, and translational science Experience with health authority interactions Experience as lead or contributing clinical pharmacologist on a successful NDA submission Familiar with GLP, GCP, and ICH requirements Practical experience in modeling and simulation Highly motivated to work and collaborate in a fast-paced, high performing team #LI-ONSITE We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. Salary range $272,400—$408,000 USD

Responsibilities

The Vice President of Pharmaceutical Sciences will lead the scientific, technical, and operational aspects of Pharmaceutical Science for R&D. This includes collaborating with drug discovery and development teams to ensure successful IND and NDA submissions.