Company Description
Axolabs is a business unit of LGC, and a leading provider of CRO / CDMO capability to the therapeutic oligonucleotide discovery and development industry. Centred out of LGC’s site in Kulmbach, Germany, Axolabs works closely with its customers to assist the identification and development of lead candidates with a broad suite of bioinformatics, biology, chemistry, manufacturing and analytical services that support discovery, pre-clinical and clinical trials and scale-up manufacture. With a track record in Nucleic Acid Therapeutics that traces back more than 20 years, Axolabs provides deep knowledge and expertise in the services it provides, working collaboratively and responsively with its clients to assist them in achieving their objectives.
Axolabs facility in Petaluma is focused on manufacturing scale-up and production to cGMP of multigram to kilograms of API for pre-clinical and clinical development. Our site in California has been involved in oligonucleotide synthesis for three decades and established the therapeutics activity in 2019. With around 70 staff and two manufacturing trains, Axolabs offers a flexible manufacturing service out of Petaluma that draws where necessary on our industry and chemical and analytical expertise in Kulmbach.
Job Description

MINIMUM QUALIFICATIONS:

• Science degree in Chemistry, Biology or similar with 2 years lab experience in manufacturing
• Must have strong organic chemistry and/or analytical chemistry knowledge, and proficiency in associated analytical techniques; HPLC, LC-MSMS or GC-MS
• Proficient in cGMP
• Solid understanding of analytical manufacturing support

PREFERRED QUALIFICATIONS:

• Experience in size exclusion, ion exchange, and reverse phase chromatography, KF, FT-IR and NMR techniques preferred
  Additional Information

• Setting up instrument sequences, while monitoring analysis and data
• Performing instrument troubleshooting, maintenance, and reporting of results for timely delivery to internal and external collaborators
• Coordinating routine and stability analysis, while driving continuous improvement via analytical methodologies
• Maintaining appropriate quality control processes and procedures to determine accuracy and precision of analysis
• Demonstrating a familiarity with GMP guidelines 21 CFR Part 210/211 and ICHQ