Autolus is looking for a motivated and detail-oriented Operator I to join our GMP manufacturing team in Stevenage. This shift-based role requires weekend working within the operational hours of 6 AM – 10 PM. As part of the Production team, you will contribute to the manufacture and delivery of Autologous cell therapies for patients. This is an excellent opportunity to develop your skills in a cleanroom environment while working within a dynamic and evolving team.

SKILLS & EXPERIENCE

• GMP manufacturing or cleanroom experience (essential) or relevant transferable skills.
• Prior experience in shift-based work (essential).
• Ability to work effectively in high-performance environments.
• Strong understanding of GxP production (essential) and knowledge of ATMP manufacturing (preferred).
• Basic awareness of environmental, health & safety requirements.
• Excellent time management, decision-making, and risk assessment skills.

• Execute GMP manufacturing processes under strict regulatory guidelines to produce high-quality cell-based products.
• Follow Standard Operating Procedures (SOPs) and Standard Work Instructions (SWIs) in compliance with Good Manufacturing Practices (GMP).
• Perform cleanroom activities, including cell culture sampling, counting, washing, activation, feeding, and harvesting.
• Support aseptic processing activities such as Magnetic Enrichment & Depletion (MACS), drug product visual inspection, and process adjustments.
• Assist with raw material transfers, environmental monitoring, labelling, reconciliation, and documentation management.
• Maintain a strong focus on safety, quality, and compliance, raising any issues proactively.
• Participate in continuous improvement (CI), root cause analysis (RCA), and corrective & preventive action (CAPA) initiatives.
• Support training and development of junior staff, contributing to a collaborative team environment.