COMPANY DESCRIPTION

Zymeworks is a publicly listed (NASDAQ:ZYME) clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeutics to improve the standard of care for difficult-to-treat diseases, including cancer, inflammation, and autoimmune disease. Zymeworks’ suite of complementary therapeutic platforms and its fully-integrated drug development engine provide the flexibility and compatibility to precisely engineer and develop antibody-based therapeutic candidates. We are a global company headquartered in Vancouver, BC, with operations in Bellevue, WA, Dublin, Ireland, Singapore and Redwood City, CA.

• Design bioanalytical methods to evaluate PK, and immunogenicity to support late stage preclinical and all stages of clinical development for Zymeworks portfolio of multispecific antibodies and ADCs.
• Oversee and manage bioanalytical method transfer, assay development and validation at contract research organizations (CROs).
• Design, oversee and manage critical reagent generation campaigns at CROs.
• Manage in-house and CRO critical reagent inventory and life cycle management.
• Ensure that bioanalytical work performed at CROs is in line with relevant regulatory guidance’s and meets the scientific needs of the program.
• Collaborate with cross-functional team members to design assays and contribute to the overall strategy to develop multispecific antibodies and ADCs.
• Writes and reviews relevant sections of regulatory and scientific documentation including Clinical Study Protocols, IBs, SOPs, Statistical Analysis Plans and Clinical Study Reports.
• Reviewing/Authoring scientific publications, abstracts, posters
• Maintains a working knowledge of pharmacology, biology, therapeutics, drug metabolism, bioanalysis, and biopharmaceutics.
• Maintain a positive, results-orientated work environment, building partnerships and modeling teamwork, and communicating to the team in an open, balanced and objective manner.
• Summarizes and presents results to supervisor in a logical manner, verbally and in written reports or presentations. May present data to project team meetings.
• Other duties as assigned.