Company Description
Welcome to AbbVie! As part of an international company with 50,000 employees worldwide and around 3,000 employees in Germany, you will have the opportunity of addressing some of tomorrows unmet medical needs in close collaboration with your colleagues. Are you passionate about improving global health care? Do you want to contribute to improving patients’ quality of life through your expertise? In a challenging work environment that offers opportunities of developing and increasing your own skills? You’ve come to the right place!
Job Description
In our Pharmaceutical development department within Product Development Science & Technology (PD S&T) at the Ludwigshafen site, you will be working in a team of talented people and experienced experts toward developing tomorrow’s products. In cutting-edge laboratories, you will be setting highest standards in the competitive field.
Moving mountains together – as Post-Doc – Freez-Thaw Studies on Biologics (all genders) (full-time, temporary for 24 months).
Product Development, Science and Technology (PDS&T) drives product development of assets which proved effective in early clinical trials and provides support for on-market products. Biologics drug substances are typically stored as frozen solutions prior to drug product manufacturing. The thawing and freezing of these solutions, particularly repeated cycles, are known to bear the risk of protein damage. Based on current knowledge of the mechanisms of freeze-thaw instability, you design, conduct and evaluate studies pushing for a deeper understanding of the dynamic mechanism in relevant formulations and publish results in peer-reviewed journals. A substantial arm of the studies will be evaluations on the influence of excipient crystallization on freeze-thaw instability.

QUALIFICATIONS

• Ph.D. in biochemistry or chemistry or related area, preferably with a background in biophysics and crystallography
• Experience with WAXS/SAXS, thermal analyses and vibrational spectroscopies preferred
• Work experience in the field of protein aggregation is advantageous
• Experience with analytical methods to detect protein denaturation and aggregation as well as to detect/characterize particles in solution is advantageous
• Affinity to work hand-on with complex analytical equipment and solve related technical problems
• Business fluent in English, German language skills of advantage
• Record of scientific initiative and creativity in research or development activities
• Capable of independently designing and executing experiments, statistical evaluation, interpreting data, and identifying appropriate follow-up strategies
  Additional Information

HERE’S HOW WE CAN MOVE MOUNTAINS TOGETHER:

• with a diverse work environment where you can have a real impact
• with an open corporate culture
• with an attractive salary
• with an intensive onboarding process with a mentor at your side
• with flexible work models for a healthy work-life balance
• with a corporate health management that offers comprehensive health and exercise programs
• with company social benefits
• with a wide range of career opportunities in an international organization
• with top-tier, attractive development opportunities
• with a strong international network
  Multiple times, we have been globally recognized as a “Great Place to Work” and we are proud to provide our employees with the flexibility to maintain a healthy work-life balance. We take our impact on the environment and our communities seriously and therefore focus on giving something back on a regular basis. We are committed to equality, equity, diversity and inclusion (EED&I) – a commitment that is fundamental to us. This includes appreciating different perspectives, creating an inclusive culture and treating all employees with dignity and respect.
  At AbbVie, your individual contributions count – help us move mountains together. Be a part of our success, grow with us and accomplish more than you could have imagined. Sounds like the perfect career opportunity for you? We look forward to receiving your application! All you need is a complete CV – we will discuss everything else with you in person.
  Any questions? Feel free to email us at TalentAcquisition.de@abbvie.com – we look forward to hearing from you!
  AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
  US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
  US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
  https://www.abbvie.com/join-us/reasonable-accommodations.htm

• Plan and perform systematic studies to dive deeper into the root causes of freeze-thaw instability of proteins
• Publish results in peer-reviewed journals and present work at internal panels and scientific conferences aligned with business objectives
• Collaborate with international multidisciplinary teams to advance project goals
• Participate in investigations on the root cause of freeze-thaw instability phenomena of development projects
• Demonstrate a high degree of responsibility in maintaining scientific standards, and safe laboratory practices
• Maintain a high level of productivity in the laboratory setting
• Proactively seek out new information in the literature and incorporate this into individual project(s) as well as the overall program