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Director/Senior Director, In Vivo Pharmacology at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
In Vivo Pharmacology, Drug Development, Translational Pharmacology, Leadership, Animal Models, Pk/Pd Principles, Data Interpretation, Regulatory Filings, Collaboration, Team Management, Research, Efficacy Studies, Mechanism Of Action, Compliance, Cro Management, Scientific Guidance
Specialization
Candidates must have a PhD in Pharmacology or related field with over 10 years of industry experience. Strong leadership skills and extensive knowledge of animal disease models and translational science are essential.
Experience Required
Minimum 10 year(s)
Technical Lead at Synoptek
Ahmedabad, gujarat, India - Full Time
Skills Needed
Dotnet Core, Dotnet Mvc, C#, Asp.Net, Angular, React, Git, Ci/Cd, Docker, Azure Functions, Logic Apps, Azure Paas, Aks, Api Gateway, Redis Cache, Sql Server
Specialization
Candidates should have a Bachelor's degree in Computer Science or a related field, with a minimum of 5 years of experience in .NET development and architecture. Proven experience in leading development teams and delivering enterprise-grade digital solutions is also required.
Experience Required
Minimum 5 year(s)
Clinical Research Associate/Senior Clinical Research Associate at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Clinical Oversight, Site Management, Cro Oversight, Data Quality, Regulatory Standards, Recruitment Tracking, Cross Functional Collaboration, Problem Solving, Communication Skills, Organizational Skills, Clinical Trial Planning, Monitoring Training, Vendor Management, Compliance, Project Management, Clinical Data Understanding
Specialization
A bachelor's degree in life sciences or a related field is required, along with experience in site selection and monitoring. Candidates should possess strong organizational skills and the ability to work independently on multiple projects.
Experience Required
Minimum 2 year(s)
Senior Scientist/Staff Scientist, Protein Science (industry experience requ at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Protein Biochemistry, Protein Engineering, Cell Culture, Protein Expression, Protein Purification, Fplc, Hplc, Membrane Proteins, Gpcrs, Automation, Data Analysis, Collaboration, Communication, Biochemical Workflows, Protein Characterization, Eukaryotic Cell Culture
Specialization
Candidates must have a PhD with a minimum of 5 years or a BS/MS with 10 years of relevant experience in biotechnology or pharmaceuticals. Proficiency in protein engineering and purification techniques, particularly for GPCRs, is required.
Experience Required
Minimum 5 year(s)
Director, Clinical Operations at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Clinical Operations, Project Management, Team Leadership, Cross Functional Collaboration, Vendor Management, Regulatory Compliance, Process Improvement, Budget Management, Risk Mitigation, Clinical Trials, Therapeutic Areas, Data Quality, Kpi Tracking, Operational Excellence, Innovation, Patient Engagement
Specialization
Candidates should have an advanced degree and a minimum of 10 years of experience in clinical operations, with a proven track record in managing global clinical programs. Strong leadership skills and the ability to collaborate across functions are essential.
Experience Required
Minimum 10 year(s)
Business Development Manager, Microsoft Dynamics 365 at Synoptek
, , United States - Full Time
Skills Needed
Business Development, Sales Execution, Negotiation, Communication, Presentation, Pipeline Development, Contract Negotiation, C Level Engagement, Relationship Building, Digital Transformation, Microsoft Dynamics 365, Power Platform, Problem Solving, Team Collaboration, Client Satisfaction, Forecast Discipline
Specialization
Candidates should have a bachelor's degree in a related field and at least 4 years of experience in enterprise software sales, particularly with Microsoft Dynamics 365. A proven track record of closing new business and engaging with C-level executives is essential.
Experience Required
Minimum 5 year(s)
Vice President, Clinical Development at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Clinical Development, Drug Development, Regulatory Affairs, Clinical Trials, Team Leadership, Communication, Collaboration, Strategic Planning, Medical Oversight, Scientific Writing, Project Management, Problem Solving, Mentoring, Entrepreneurial Mindset, Innovative Trial Design, Cross Functional Leadership
Specialization
Candidates must have an MD or MD/PhD and at least 10 years of experience in Clinical Development. A proven track record in drug development, particularly in rare diseases, and excellent communication and leadership skills are essential.
Experience Required
Minimum 10 year(s)
Director, Medical Writing at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Medical Writing, Clinical Documents, Regulatory Submissions, Leadership, Collaboration, Attention To Detail, Problem Solving, Communication, Project Management, Drug Development, Ich Guidelines, Fda Guidelines, Ema Guidelines, Mentoring, Strategic Direction
Specialization
A Bachelor’s degree in life sciences is required, with an advanced degree preferred. Candidates should have over 10 years of medical writing experience in the biopharmaceutical industry, particularly with clinical and regulatory documents.
Experience Required
Minimum 10 year(s)
Director, Regulatory Affairs at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Regulatory Affairs, Project Management, Communication Skills, Drug Development, Cross Functional Leadership, Regulatory Strategy, Ind Submissions, Cta Submissions, Fda Interactions, Risk Management, Collaboration, Attention To Detail, Mentoring, Strategic Thinking, Problem Solving
Specialization
Bachelor’s degree in life sciences or a related field is required, with an advanced degree preferred. Candidates should have 10+ years of experience in Regulatory Affairs within the biopharmaceutical industry, including leading IND and/or CTA submissions.
Experience Required
Minimum 10 year(s)
Senior Director, GMP Quality Assurance at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Gmp Quality Assurance, Quality Oversight, Regulatory Compliance, Deviation Management, Change Control, Capa, Batch Disposition, Sop Authoring, Quality Metrics, Auditing, Vendor Qualification, Risk Based Quality Oversight, Collaboration, Communication, Attention To Detail, Organizational Skills
Specialization
Candidates should have a bachelor's degree in life sciences or a related field, with an advanced degree preferred. A minimum of 15 years of experience in Quality Assurance within the biopharmaceutical industry is required, with a focus on GMP QA.
Experience Required
Minimum 10 year(s)
Shipping Coordinator (Logistics / Shipment) at EA RECRUITMENT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Working Experience, Availability
Qualification
Graduate
Experience Required
Minimum 2 year(s)
Centre Leader at MYNT EDUCATION PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Leadership, Leadership Skills, Early Childhood Education
Qualification
Diploma
Audit Partner (Mid-Tier Firm) at RECRUIT EXPERT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Financial Reporting, Leadership Skills, Auditing Standards, Qualified Chartered Accountant
Specialization
A qualified chartered accountant (ca singapore) and isca member possessing an official public accountant registration with acra along with a current practising certificate.
Qualification
Trade Certificate
Experience Required
Minimum 10 year(s)
BIM Coordinator (M&E) at RECRUIT EXPERT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Revit, Navisworks
Specialization
Possess bim certificate.
Qualification
Trade Certificate
Experience Required
Minimum 2 year(s)
M&E / Mechanical Project Engineer (Project I EPC I Chemical Process Plant) at EA RECRUITMENT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Codes, Epc, Commissioning, Construction
Specialization
Chemical, Engineering
Qualification
Graduate
Control Engineer (Global High-Tech Engineering; Semiconductor;Listed) at LICO RESOURCES PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Mechatronics, Python, Matlab, System Identification, Control Theory, Motor Control, Sensors, Actuators
Specialization
Electrical, Engineering, Mechatronics
Qualification
Graduate
Cashier at Curate Kitchen Pte Ltd
Singapore 757432, , Singapore - Full Time
Skills Needed
Payments, Interpersonal Skills, Customer Service
Specialization
Possession of a valid food safety certificate will be an added advantage.
Qualification
Trade Certificate
Experience Required
Minimum 1 year(s)
Facilities Engineer (Building Services) at RECRUIT EXPERT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Good Communication Skills
Specialization
Electrical, Electrical Engineering, Engineering
Qualification
Diploma
Experience Required
Minimum 3 year(s)
Safety Officer (WSHO I LTA Projects) at EA RECRUITMENT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Availability
Qualification
Diploma
Experience Required
Minimum 1 year(s)
Senior Software Engineer (Machine Vision / GUI / Industrial Automation) at EA RECRUITMENT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Wpf, Motion, Computer Engineering, Availability, Framework
Specialization
Engineering
Qualification
Graduate
Director/Senior Director, In Vivo Pharmacology at Septerna
South San Francisco, California, United States -
Full Time

Start Date

Immediate

Expiry Date

10 Jan, 26

Salary

270000.0

Posted On

13 Oct, 25

Experience

10 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

No

Skills

In Vivo Pharmacology, Drug Development, Translational Pharmacology, Leadership, Animal Models, PK/PD Principles, Data Interpretation, Regulatory Filings, Collaboration, Team Management, Research, Efficacy Studies, Mechanism-of-Action, Compliance, CRO Management, Scientific Guidance

Industry

Biotechnology

Description
Septerna is a biotechnology company based in South San Francisco, CA on a mission to develop life-changing medicines for patients with the vision to become the industry-leading G protein-coupled receptor (GPCR)-focused drug discovery company. The company’s Native Complex Platform™ recapitulates GPCRs with their native structure, function, and dynamics outside of the cellular context. This approach enables novel access to modern structural and screening technologies used in industrial-scale drug discovery for the entire class of GPCRs. Septerna has an emerging pipeline of GPCR-targeted small molecule programs with potential for growth to target many GPCRs that have been undruggable and unexploited to date. We are excited to expand our multidisciplinary team of individuals focused on creating revolutionary medicines to address the unmet needs of patients. At Septerna we strive to embrace diversity of thought, expertise, and background through collaboration. To join our ambitious team, be prepared to bring your real self to work every day; grow and learn from a talented team of drug hunters, scientists, and business professionals; and contribute your passion, creativity, and energy to accomplish our mission. We share a fearless pursuit of ground-breaking innovations and cultivate an environment where our employees succeed by learning from each other and working as a team. We are committed to the development of meaningful therapeutics for patients with indications of high unmet need. This is a tremendous opportunity to work with talented individuals on the frontlines of therapeutic discovery and development. You will directly help move therapies through preclinical research, positioning them for success in the clinic. The successful candidate will add their passion, unique talents, and expertise to a dynamic team motivated to discover new disease-modifying therapeutics for patients in a fast-paced environment. For more information see: www.septerna.com. The Role: We are seeking a highly experienced and strategic Director/Senior Director of In Vivo Pharmacology to lead preclinical pharmacology efforts and support the discovery and early development of promising drug candidates through in vivo proof-of-concept studies. This hands-on leadership role will oversee the design and execution of in vivo pharmacology and pharmacokinetics/pharmacodynamics (PK/PD) studies in relevant animal disease models. The successful candidate will direct a small team of talented scientists and research associates working in our in-house vivarium and managing relationships with external CROs and academic collaborators. The ideal candidate will possess deep expertise in translational pharmacology, strong leadership skills, and the ability to contribute as a project team leader on cross-functional drug discovery teams. Key Responsibilities: Lead the design, execution, and interpretation of in vivo efficacy, mechanism-of-action, and PK/PD studies in animal models of disease Develop and refine animal models that reflect human disease pathophysiology for multiple therapeutic areas Provide scientific and strategic leadership for a team of in vivo pharmacologists and research associates Be engaged in critical experiments, including scientific and technical guidance on surgical procedures and phenotypic assessments, and data interpretation. Collaborate cross-functionally with discovery biology, DMPK, chemistry, toxicology, and clinical pharmacology teams to advance compounds from discovery through IND-enabling studies Oversee vivarium operations of their team ensuring compliance with IACUC protocols and regulatory standards Support studies informing dose selection and prediction of clinical outcomes Manage external CRO relationships and academic collaborations Author and review preclinical study reports and regulatory submissions (IB, IND) Serve as project team leader or in vivo pharmacology representative on drug discovery teams, contributing to program strategy and decision-making Qualifications: PhD in Pharmacology, Physiology, or related life sciences discipline with 10+ years of industry experience in in vivo pharmacology and drug development. Experience across multiple therapeutic areas preferred (e.g., endocrine, inflammation, metabolic, CNS). Proven track record of people management, leading in vivo pharmacology teams and cross-functional project teams in a biopharmaceutical setting. Proven ability to manage CRO relationships and external collaborations. Extensive hands-on experience and knowledge of animal disease models, experimental design, and translational science. Strong background in PK/PD principles and data interpretation. Experience contributing to regulatory filings and understanding of regulatory expectations for nonclinical studies. Excellent leadership, mentoring, communication, and interpersonal skills. The anticipated salary range for candidates who will work in South San Francisco, CA is $250,000 - $270,000. Individual pay may vary based on additional factors, including, and without limitation, job-related skills, experience, work location and relevant education or training. Septerna's compensation package also includes benefits, stock options, and annual target bonus for full-time positions. We are an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited. Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited. We are an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. Septerna participates in the E-Verify program. California Consumer Privacy Act Privacy Notice For Job Applicants. If you are a California resident, click here for our CCPA Notice.
Responsibilities
Lead the design and execution of in vivo pharmacology studies and manage a team of scientists. Collaborate with cross-functional teams to advance drug candidates through preclinical research.
Director/Senior Director, In Vivo Pharmacology at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
In Vivo Pharmacology, Drug Development, Translational Pharmacology, Leadership, Animal Models, Pk/Pd Principles, Data Interpretation, Regulatory Filings, Collaboration, Team Management, Research, Efficacy Studies, Mechanism Of Action, Compliance, Cro Management, Scientific Guidance
Specialization
Candidates must have a PhD in Pharmacology or related field with over 10 years of industry experience. Strong leadership skills and extensive knowledge of animal disease models and translational science are essential.
Experience Required
Minimum 10 year(s)
Technical Lead at Synoptek
Ahmedabad, gujarat, India - Full Time
Skills Needed
Dotnet Core, Dotnet Mvc, C#, Asp.Net, Angular, React, Git, Ci/Cd, Docker, Azure Functions, Logic Apps, Azure Paas, Aks, Api Gateway, Redis Cache, Sql Server
Specialization
Candidates should have a Bachelor's degree in Computer Science or a related field, with a minimum of 5 years of experience in .NET development and architecture. Proven experience in leading development teams and delivering enterprise-grade digital solutions is also required.
Experience Required
Minimum 5 year(s)
Clinical Research Associate/Senior Clinical Research Associate at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Clinical Oversight, Site Management, Cro Oversight, Data Quality, Regulatory Standards, Recruitment Tracking, Cross Functional Collaboration, Problem Solving, Communication Skills, Organizational Skills, Clinical Trial Planning, Monitoring Training, Vendor Management, Compliance, Project Management, Clinical Data Understanding
Specialization
A bachelor's degree in life sciences or a related field is required, along with experience in site selection and monitoring. Candidates should possess strong organizational skills and the ability to work independently on multiple projects.
Experience Required
Minimum 2 year(s)
Senior Scientist/Staff Scientist, Protein Science (industry experience requ at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Protein Biochemistry, Protein Engineering, Cell Culture, Protein Expression, Protein Purification, Fplc, Hplc, Membrane Proteins, Gpcrs, Automation, Data Analysis, Collaboration, Communication, Biochemical Workflows, Protein Characterization, Eukaryotic Cell Culture
Specialization
Candidates must have a PhD with a minimum of 5 years or a BS/MS with 10 years of relevant experience in biotechnology or pharmaceuticals. Proficiency in protein engineering and purification techniques, particularly for GPCRs, is required.
Experience Required
Minimum 5 year(s)
Director, Clinical Operations at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Clinical Operations, Project Management, Team Leadership, Cross Functional Collaboration, Vendor Management, Regulatory Compliance, Process Improvement, Budget Management, Risk Mitigation, Clinical Trials, Therapeutic Areas, Data Quality, Kpi Tracking, Operational Excellence, Innovation, Patient Engagement
Specialization
Candidates should have an advanced degree and a minimum of 10 years of experience in clinical operations, with a proven track record in managing global clinical programs. Strong leadership skills and the ability to collaborate across functions are essential.
Experience Required
Minimum 10 year(s)
Business Development Manager, Microsoft Dynamics 365 at Synoptek
, , United States - Full Time
Skills Needed
Business Development, Sales Execution, Negotiation, Communication, Presentation, Pipeline Development, Contract Negotiation, C Level Engagement, Relationship Building, Digital Transformation, Microsoft Dynamics 365, Power Platform, Problem Solving, Team Collaboration, Client Satisfaction, Forecast Discipline
Specialization
Candidates should have a bachelor's degree in a related field and at least 4 years of experience in enterprise software sales, particularly with Microsoft Dynamics 365. A proven track record of closing new business and engaging with C-level executives is essential.
Experience Required
Minimum 5 year(s)
Vice President, Clinical Development at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Clinical Development, Drug Development, Regulatory Affairs, Clinical Trials, Team Leadership, Communication, Collaboration, Strategic Planning, Medical Oversight, Scientific Writing, Project Management, Problem Solving, Mentoring, Entrepreneurial Mindset, Innovative Trial Design, Cross Functional Leadership
Specialization
Candidates must have an MD or MD/PhD and at least 10 years of experience in Clinical Development. A proven track record in drug development, particularly in rare diseases, and excellent communication and leadership skills are essential.
Experience Required
Minimum 10 year(s)
Director, Medical Writing at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Medical Writing, Clinical Documents, Regulatory Submissions, Leadership, Collaboration, Attention To Detail, Problem Solving, Communication, Project Management, Drug Development, Ich Guidelines, Fda Guidelines, Ema Guidelines, Mentoring, Strategic Direction
Specialization
A Bachelor’s degree in life sciences is required, with an advanced degree preferred. Candidates should have over 10 years of medical writing experience in the biopharmaceutical industry, particularly with clinical and regulatory documents.
Experience Required
Minimum 10 year(s)
Director, Regulatory Affairs at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Regulatory Affairs, Project Management, Communication Skills, Drug Development, Cross Functional Leadership, Regulatory Strategy, Ind Submissions, Cta Submissions, Fda Interactions, Risk Management, Collaboration, Attention To Detail, Mentoring, Strategic Thinking, Problem Solving
Specialization
Bachelor’s degree in life sciences or a related field is required, with an advanced degree preferred. Candidates should have 10+ years of experience in Regulatory Affairs within the biopharmaceutical industry, including leading IND and/or CTA submissions.
Experience Required
Minimum 10 year(s)
Senior Director, GMP Quality Assurance at Septerna
South San Francisco, California, United States - Full Time
Skills Needed
Gmp Quality Assurance, Quality Oversight, Regulatory Compliance, Deviation Management, Change Control, Capa, Batch Disposition, Sop Authoring, Quality Metrics, Auditing, Vendor Qualification, Risk Based Quality Oversight, Collaboration, Communication, Attention To Detail, Organizational Skills
Specialization
Candidates should have a bachelor's degree in life sciences or a related field, with an advanced degree preferred. A minimum of 15 years of experience in Quality Assurance within the biopharmaceutical industry is required, with a focus on GMP QA.
Experience Required
Minimum 10 year(s)
Shipping Coordinator (Logistics / Shipment) at EA RECRUITMENT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Working Experience, Availability
Qualification
Graduate
Experience Required
Minimum 2 year(s)
Centre Leader at MYNT EDUCATION PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Leadership, Leadership Skills, Early Childhood Education
Qualification
Diploma
Audit Partner (Mid-Tier Firm) at RECRUIT EXPERT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Financial Reporting, Leadership Skills, Auditing Standards, Qualified Chartered Accountant
Specialization
A qualified chartered accountant (ca singapore) and isca member possessing an official public accountant registration with acra along with a current practising certificate.
Qualification
Trade Certificate
Experience Required
Minimum 10 year(s)
BIM Coordinator (M&E) at RECRUIT EXPERT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Revit, Navisworks
Specialization
Possess bim certificate.
Qualification
Trade Certificate
Experience Required
Minimum 2 year(s)
M&E / Mechanical Project Engineer (Project I EPC I Chemical Process Plant) at EA RECRUITMENT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Codes, Epc, Commissioning, Construction
Specialization
Chemical, Engineering
Qualification
Graduate
Control Engineer (Global High-Tech Engineering; Semiconductor;Listed) at LICO RESOURCES PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Mechatronics, Python, Matlab, System Identification, Control Theory, Motor Control, Sensors, Actuators
Specialization
Electrical, Engineering, Mechatronics
Qualification
Graduate
Cashier at Curate Kitchen Pte Ltd
Singapore 757432, , Singapore - Full Time
Skills Needed
Payments, Interpersonal Skills, Customer Service
Specialization
Possession of a valid food safety certificate will be an added advantage.
Qualification
Trade Certificate
Experience Required
Minimum 1 year(s)
Facilities Engineer (Building Services) at RECRUIT EXPERT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Good Communication Skills
Specialization
Electrical, Electrical Engineering, Engineering
Qualification
Diploma
Experience Required
Minimum 3 year(s)
Safety Officer (WSHO I LTA Projects) at EA RECRUITMENT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Availability
Qualification
Diploma
Experience Required
Minimum 1 year(s)
Senior Software Engineer (Machine Vision / GUI / Industrial Automation) at EA RECRUITMENT PTE LTD
Singapore, , Singapore - Full Time
Skills Needed
Wpf, Motion, Computer Engineering, Availability, Framework
Specialization
Engineering
Qualification
Graduate