ADC Drug Linker Analytical Lead

at  AstraZeneca

Job Title: ADC Drug Linker Analytical Lead
Introduction to role:
Join our Chemical Development team within Pharmaceutical Technology & Development, where we push the boundaries of science to deliver medicines to patients. We are growing and have an exciting opportunity for an Antibody Drug Conjugate (ADC) Drug Linker Analytical Lead to join us in delivering the next generation of medicines. Be part of a team that is committed to innovation, continuous improvement, sustainability, automation and lifelong learning.
Accountabilities:
As an ADC Drug Linker Analytical Lead, you will develop control strategies, support drug substance manufactures for clinical and commercial supply, and play a key part in delivering regulatory submissions. You will interact with stakeholders across project management, quality and regulatory departments ensuring success in CMC project delivery. You will also contribute to Chemical Development’s ambition to support and grow careers in science by leading successful initiatives that include driving forums for shared learning, as well as coaching and developing analytical scientists across the department.

Essential Skills/Experience:

• BSc/PhD level education in a relevant discipline and significant experience within a Research, Development and Manufacturing environment within the pharmaceutical industry
• Experience of technical supervision, coaching and mentoring or leading small teams of people or significant scientific projects
• A thorough understanding of key analytical techniques, including chromatography
• Experience in leading complex projects (including managing resourcing, risks, and stakeholders)
• Experience in building the regulatory control strategy for drug substance or drug products
• Experience in supporting clinical and/or commercial manufacture and/or working with contract manufacturing organisations
• Ability to think and operate across functional boundaries, challenge the status quo and seek opportunities for business improvement
• A thorough appreciation of the principles and management of Safety, Health and Environment (SHE) and Good Manufacturing Practice (cGMP)

Desirable Skills/Experience

• A broad understanding of the overall drug development process from discovery through to launch in ADCs
• Experience in delivering CMC content, or contributions to regulatory filings for clinical and commercial drug substance
• Excellent communication and strategic influencing skills across interfaces of discipline, culture, and expertise both internally and externally
• The ability to lead improvement projects confidently and successfully
• Ability to analyse and interpret complex situations and provide clear strategic direction

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
At AstraZeneca, we are driven by our commitment to deliver accelerated growth and to make people’s lives better. We are part of an inclusive and giving community, where we support each other on our journeys. We are intellectually stimulated by constant learning. There’s potential for multiple, global careers and great rewards, for those who embrace the diverse opportunities. We are committed to making a difference beyond patients, pioneering AstraZeneca’s sustainability strategy. Have the opportunity to be a key contributor to Zero Carbon by 2025 and carbon negative across the entire value chain by 2030.
Ready to make an impact on society through our sustainability goals? Apply now to join our Operations team as an ADC Drug Linker Analytical Lead

Please refer the Job description for details