Senior Research Scientist / Associate Principal Scientist - Isotope Chemistry

at  AstraZeneca

Join AstraZeneca, a global leader in pharmaceutical innovation, where we turn ideas into life-changing medicines. We are currently seeking a Senior Research Scientist or an Associate Principle Scientist to join our Isotope Chemistry Team, part of Early Chemical Development, in Gothenburg, Sweden. The Isotope Chemistry Team delivers high-quality tritium, C-14, and stable isotope labeled compounds through the use of novel chemistry, innovative routes, and creative solutions. The laboratory is a companywide asset for the non-GMP manufacture of radiolabeled and stable isotope labeled compounds. It supports projects from target identification to single compound selection to clinical phases and post marketing support for all therapy areas in the portfolio.
The isotope chemistry team supports the projects with the highest priority and urgent needs in the AZ portfolio and has access to top-quality labs and equipment.

ACCOUNTABILITIES:

As a member of the Isotope Chemistry Team, you will work closely with scientists in drug projects to develop safe, efficient, and cost-effective synthesis routes to labeled drug candidates and tool compounds. You will, with a strong emphasis on safety, health, and environmental aspects, explore and develop experimental strategies, troubleshoot problems, and synthesize labeled organic molecules. You will also plan, prioritise, and perform your own work and actively collaborate with the drug project teams. In this role, you will demonstrate your expertise in synthetic and analytical chemistry, as well as, purification techniques and provide stringent documentation of experimental results in an electronic lab journal. Publishing novel work in peer reviewed journals will also be part of your role.

ESSENTIAL SKILLS/EXPERIENCE:

• Ph.D. degree or equivalent in Organic Chemistry
• Strong collaboration and communication skills
• Strong theoretical and practical knowledge of organic chemistry
• Ability to independently design, plan, and execute multistep syntheses
• Creativity in handling a wide range of synthetic challenges
• Ability to coach peers for improved individual and team performance and development
• A good communicator with experience in interacting effectively across disciplines
• Work collaboratively across boundaries
• Curious and innovative

DESIRABLE SKILLS/EXPERIENCE:

• Previous work with radioactivity is not required but would be advantageous
  At AstraZeneca, we follow the science to explore and innovate. We are working towards treating, preventing, modifying and even curing some of the world’s most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference by fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. It’s our combination of curiosity and courage that drives us, inspired by the possibility of doing things that have never been done before.

Please refer the Job description for details