Associate Principal Scientist - Drug Product Development

at  Pharmaron

Job Introduction We are looking for:
An Associate Principal Scientist, a subject matter expert, to solve complex drug product development issues for assigned projects and support the execution of formulation development programs involving phase-appropriate formulations and processes to support clinical studies or client needs.

At Pharmaron we offer:

• Vibrant and dynamic employment – we are a highly specialised, growth company operating in a critical sector of the economy – our future is strong and exciting!
• Opportunities to develop your skills and yourself – our rapid growth brings greater opportunities for you to learn and grow faster!
• A great team where we all support each other – enjoy your work – after all you spend about a third of your time here!

REQUIREMENTS:

• Degree or equivalent and in Pharmacy, Pharmaceutical Science, or Chemistry related discipline and evidence of strong academic/industrial experience and achievement with at least 5 years in applicable role, operating in GMP environment
• Evidence of successful application of technical skill sets to resolve high complexity formulation challenges
• Evidence of ability to effectively contribute to multi-disciplinary scientific teams and ability to effectively lead and supervise staff, as well as proven performance management skills.
• Drug product formulation and development knowledge and sound knowledge of regulatory and cGMP requirements
• Cross functional project management experience. As well as numerical, analytical, data recording, interpretation and management skills
• Effective written and oral communication skills, including the ability to effectively present scientific findings to colleagues
• Effective organizational, planning and time management skills
• Excellent interpersonal and influencing skills
• IT skills with a good working knowledge of MS Office
• Excellent motivation and team building skills and a positive “can do” attitude
• Results oriented with a dedicated, unwavering desire to do/deliver the best
• Good work ethic related to confidentiality and non-disclosure of intellectual property
• Evidence of strong motivation for continued learnings, including advanced pharmaceutical/analytical/physical chemistry technical capabilities

Key roles and responsibilities:

• In a multidisciplinary environment, design, plan and execute core experiments, interpret results, and plan additional experiments in a timely manner for assigned projects and/ or initiatives, with limited guidance from manager or scientific supervisor.
• Document and report results of all experiments in a manner consistent with department practices and governing policies, as applicable. May conduct second scientist review of experimental documentation.
• Demonstrate expertise in the core formulation laboratory skills required to support development and/or scale up of drug product manufacturing processes. Such skills include, but are not limited to, expert application of core laboratory techniques and instrumentation to positively impact drug product development. From time to time, use of selected higher end instrumentation or methodologies with supervisor guidance may be required
• Actively participate in the development of new technologies or methodologies, as appropriate within the functional area.
• Effectively communicate, co-ordinate and collaborate with cross-functional project groups to ensure that scientific work is appropriately documented such that the broader collaborative input and efforts are combined to maximum effect in the production of reports, manuscripts and presentation.
• Document and report results of all experiments in a manner consistent with department practices and governing policies, as applicable.
• Contribute to effective team planning and mentor less experienced staff on core functional technical and procedural matters as opportunities arise.
• May mentor junior scientists.
• Conduct work and studies within established key workflows and/ or regulations pertinent to the individual’s specific workgroup, as described by SOPs, corporate policies and external regulatory guidance(e.g. GxP, ICH, etc).
• The role requires meticulous attention to detail and all work to be conducted strictly in accordance with company Policies and Procedures and Standard Operating Procedures.
• Work efficiently and tidily such that work is carried out in a well-planned, organised and timely manner.
• Ensure that any operating practice or instrument defect, which may affect safety at work, is brought to the attention of Management.
• Encourage continuous improvement through an effective Quality Management System (QMS) striving to improve processes and practices.
• Promote and contribute to a best in class Quality culture and reputation based on collaboration.
• Promote leadership colaboration and employee engagement with the same Quality goals ensuring GMP compliance.
• Responsible for maintaining own training file.

Our Company: “We are a dynamic, fast-growing company, with an enviable reputation for leading edge science, offering contract research services to some of the world’s leading pharmaceutical companies, solving what were believed to be unsolvable scientific challenges”.We believe in our ability to relentlessly push forward the boundaries of scientific excellence, delivering solutions for our clients, always operating ethically and with integrity. We take pride in our professionalism and commitment to always deliver our very best work.Pharmaron acquired the Hoddesdon campus, consisting of several purpose built scientific and administrative buildings together with a purpose built conference area in February 2017. The research building has more than 5,000m2 of premier R&D space and houses an established Process Chemistry, Analytical Chemistry and Drug Discovery teams. In addition, a Formulation Development team was also recently established. The Hoddesdon site has state-of-the-art Good Manufacturing Practice (GMP) standard facilities for the development of Active Pharmaceutical Ingredients (API), Formulation Development (FD) and Process Chemistry (PC).

• We offer a competitive salary and a progressive and comprehensive suite of employee benefits.
• We offer state of the art working environment on site.
• We offer the opportunity for growth and development and will support funding for relevant training and development programmes.

Why Should You Apply?

• This is an opportunity for you as an Associate Principal Scientist professional to make a real impact in a highly scientific and regulated environment, demonstrate leadership, ambition and the desire to grow with the department.
• Build and shape your career in an environment that sets and commits to the highest standards.
• To be part of a team who support each other, embrace and solve technical challenges and put excellence at the heart of all that we do.

Pharmaron is a premier R&D service company supporting the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities having established diverse drug R&D service capabilities, ranging from synthetic, medicinal, and analytical chemistry, biology, DMPK, pharmacology, drug safety assessment, radiochemistry and isotopically labelled metabolism, chemical & pharmaceutical development to clinical development. With operations in China, US and UK staffed by over 19,000 employees, Pharmaron has an excellent track record in the delivery of R&D solutions to its partners in North America, Europe, Japan, and China

Key roles and responsibilities:

• In a multidisciplinary environment, design, plan and execute core experiments, interpret results, and plan additional experiments in a timely manner for assigned projects and/ or initiatives, with limited guidance from manager or scientific supervisor.
• Document and report results of all experiments in a manner consistent with department practices and governing policies, as applicable. May conduct second scientist review of experimental documentation.
• Demonstrate expertise in the core formulation laboratory skills required to support development and/or scale up of drug product manufacturing processes. Such skills include, but are not limited to, expert application of core laboratory techniques and instrumentation to positively impact drug product development. From time to time, use of selected higher end instrumentation or methodologies with supervisor guidance may be required
• Actively participate in the development of new technologies or methodologies, as appropriate within the functional area.
• Effectively communicate, co-ordinate and collaborate with cross-functional project groups to ensure that scientific work is appropriately documented such that the broader collaborative input and efforts are combined to maximum effect in the production of reports, manuscripts and presentation.
• Document and report results of all experiments in a manner consistent with department practices and governing policies, as applicable.
• Contribute to effective team planning and mentor less experienced staff on core functional technical and procedural matters as opportunities arise.
• May mentor junior scientists.
• Conduct work and studies within established key workflows and/ or regulations pertinent to the individual’s specific workgroup, as described by SOPs, corporate policies and external regulatory guidance(e.g. GxP, ICH, etc).
• The role requires meticulous attention to detail and all work to be conducted strictly in accordance with company Policies and Procedures and Standard Operating Procedures.
• Work efficiently and tidily such that work is carried out in a well-planned, organised and timely manner.
• Ensure that any operating practice or instrument defect, which may affect safety at work, is brought to the attention of Management.
• Encourage continuous improvement through an effective Quality Management System (QMS) striving to improve processes and practices.
• Promote and contribute to a best in class Quality culture and reputation based on collaboration.
• Promote leadership colaboration and employee engagement with the same Quality goals ensuring GMP compliance.
• Responsible for maintaining own training file

Our Company: “We are a dynamic, fast-growing company, with an enviable reputation for leading edge science, offering contract research services to some of the world’s leading pharmaceutical companies, solving what were believed to be unsolvable scientific challenges”.We believe in our ability to relentlessly push forward the boundaries of scientific excellence, delivering solutions for our clients, always operating ethically and with integrity. We take pride in our professionalism and commitment to always deliver our very best work.Pharmaron acquired the Hoddesdon campus, consisting of several purpose built scientific and administrative buildings together with a purpose built conference area in February 2017. The research building has more than 5,000m2 of premier R&D space and houses an established Process Chemistry, Analytical Chemistry and Drug Discovery teams. In addition, a Formulation Development team was also recently established. The Hoddesdon site has state-of-the-art Good Manufacturing Practice (GMP) standard facilities for the development of Active Pharmaceutical Ingredients (API), Formulation Development (FD) and Process Chemistry (PC).

• We offer a competitive salary and a progressive and comprehensive suite of employee benefits.
• We offer state of the art working environment on site.
• We offer the opportunity for growth and development and will support funding for relevant training and development programmes