Associate Scientist

at  Gilead Sciences

Oxford, England, United Kingdom -

Start DateExpiry DateSalaryPosted OnExperienceSkillsTelecommuteSponsor Visa
Immediate06 May, 2025Not Specified06 Feb, 2025N/APurification,Mammalian Cell Culture,Sequence Analysis,Protein Design,Communication Skills,Spr,Protein Expression,Biochemistry,Molecular BiologyNoNo
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Description:

For Current Gilead Employees and Contractors:
Please log onto your
Internal Career Site
to apply for this job.
At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
Job Description
Associate Scientist – Protein Therapeutics
Position Overview:
We are seeking a highly motivated and enthusiastic individual to join our innovative team of scientists, contributing to the development of novel protein therapeutics. This role focuses on antibody engineering and development, with the goal of discovering transformative therapies for autoimmune diseases. You’ll work in a collaborative and dynamic environment, closely partnering with both internal and external teams, while gaining hands-on experience in cutting-edge protein engineering techniques.
This position offers a unique opportunity to work under the guidance of an experienced senior scientist, fostering mentorship and professional growth. If you are excited about learning and applying your skills in a fast-paced, impactful research environment, we encourage you to apply.
Role Purpose:
To contribute to the design and development of novel protein therapeutics, which will support early research all the way through to lead candidate nomination for pre-clinical studies.

Key Responsibilities:

  • Utilize molecular biology cloning strategies to design, engineer, and express proteins and antibodies of interest
  • Recombinant protein expression/production, predominantly using mammalian platforms, using small-scale expression processes through to large-scale preparations (e.g., affinity chromatography, and prep-SEC using ÄKTA purification systems)
  • Biophysical characterisation of proteins using SDS-PAGE, HPLC, and DLS, and functional characterisation using BLI and SPR
  • Engineer proteins and antibodies for lead therapeutic identification and downstream clinical development
  • Analyze and troubleshoot experimental data to support pipeline progression
  • Stay updated with scientific literature and advances in protein engineering to incorporate best practices into your work

Ideal Qualifications:
We value diverse perspectives and contributions to our mission. Below are the qualifications and skills we are looking for in this role:

Minimum Education & Experience:

  • BSc or MSc degree in Molecular Biology or Biochemistry (or a related discipline) with hands-on laboratory experience
  • Proficiency in molecular cloning techniques and experienced in mammalian cell culture and recombinant protein expression
  • Experience with protein design, production, and biophysical characterization, including SPR

Skills and Attributes:

  • Strong analytical and practical skills, with high attention to detail demonstrated through academic or research achievements
  • Self-motivated and enthusiastic about solving problems and contributing to project pipelines
  • Team player with excellent collaboration skills and experience working in multidisciplinary teams
  • Effective written and verbal communication skills
  • Flexible and adaptable to shifting priorities, with a demonstrated ability to learn quickly in a fast-paced research environment.

Desirable Experience:

  • Familiarity with sequence analysis or molecular biology software
  • Exposure to development of protein expression, purification, and biophysical characterization workflows
  • Familiarity with approaches to molecular modelling, particularly relating to the design and optimisation of antibody sequences

What We Offer:

  • A supportive and collaborative team environment where innovation thrives
  • Mentorship from a senior scientist, offering career development and learning opportunities
  • The chance to work on impactful projects aimed at transforming therapeutic options for autoimmune diseases
  • Exposure to state-of-the-art techniques and technologies in protein and antibody engineering

Equal Employment Opportunity (EEO)
It is the policy of Gilead Sciences, Inc. and its subsidiaries and affiliates (collectively “Gilead” or the “Company") to recruit select and employ the most qualified persons available for positions throughout the Company. Except if otherwise provided by applicable law, all employment actions relating to issues such as compensation, benefits, transfers, layoffs, returns from layoffs, company-sponsored training, education assistance, social and recreational programs are administered on a non-discriminatory basis (i.e. without regard to protected characteristics or prohibited grounds, which may include an individual’s gender, race, color, national origin, ancestry, religion, creed, physical or mental disability, marital status, sexual orientation, medical condition, veteran status, and age, unless such protection is prohibited by federal, state, municipal, provincial, local or other applicable laws). Gilead also prohibits discrimination based on any other characteristics protected by applicable laws.
For Current Gilead Employees and Contractors:
Please log onto your
Internal Career Site
to apply for this job

Responsibilities:

  • Utilize molecular biology cloning strategies to design, engineer, and express proteins and antibodies of interest
  • Recombinant protein expression/production, predominantly using mammalian platforms, using small-scale expression processes through to large-scale preparations (e.g., affinity chromatography, and prep-SEC using ÄKTA purification systems)
  • Biophysical characterisation of proteins using SDS-PAGE, HPLC, and DLS, and functional characterisation using BLI and SPR
  • Engineer proteins and antibodies for lead therapeutic identification and downstream clinical development
  • Analyze and troubleshoot experimental data to support pipeline progression
  • Stay updated with scientific literature and advances in protein engineering to incorporate best practices into your wor


REQUIREMENT SUMMARY

Min:N/AMax:5.0 year(s)

Information Technology/IT

IT Software - Application Programming / Maintenance

Software Engineering

BSc

Biology

Proficient

1

Oxford, United Kingdom