Bioanalytical Associate Technical Specialist - DMPK

at  Charles River Laboratories

Req ID #: 223866
Saffron Walden, England, GB
3rd
Full time
For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

SKILLS AND EXPERIENCE

• BSc in a scientific discipline.
• Prior internship / work experience / shadowing.
• Previous work experience at similar CROs / pharma / biotech companies is advantageous.
• Effective communicator.
• Works effectively as part of a team.
• Attention to detail.
• Strong desire to develop a lab-based career discovering new medicines.

• You will be processing biological samples to determine the concentration of novel compounds designed to treat a range of medical conditions. This data is used to select the compounds with the best chance of meeting all the criteria to become a new drug. Attention to detail, accuracy and precision are key
• You will be using mass spectrometers to detect each compound.
• Full training will be given in every step of the process, from developing and optimising the detection methods, to sample and data processingAs your confidence in using and understanding the instruments grows you will also perform routine instrument validation and maintenance dutiesYou will maintain a safe working environment, and be expected to be an active participant on the general laboratory housekeeping rota’s.
• The data you generate will be used to determine the pharmacokinetic (PK) profile of compounds and understand the relationship between concentration and effect (pharmacokinetic and pharmacodynamic (PK/PD) relationships), and in support of predicting the dose required in humans to have the desired outcome whilst maintaining safety margin.