CAR-T Clinical Fellow – Haematology

at  University College London Hospitals NHS Foundation Trust

This role is set within the department of malignant haematology at UCLH with a focus on cellular therapy (including CAR-T) in accordance with JACIE accreditation standards and NHSE guidance. The T-cell Immunotherapy service at UCLH is undergoing significant expansion and the post-holder will be involved in the delivery of (1) licenced/NHSE CAR T-cell products; (2) the academic and commercial CAR T-cell trial portfolio and (3) a portfolio of TCR-transduced T-cell and Tumour Infiltrating Lymphocyte (TIL) therapies for solid tumours which we hope to further cultivate and develop through the appointments.
There will be training in trial design and delivery through involvement in Tumour Management Group meetings for the academic trial portfolio alongside attendance at Site Initiation Visits for new studies. Training regarding the function of apheresis and the stem cell lab will also be provided.
The appointment will be initially for a period of 1 year with the potential for renewal on an annual basis. The roles will provide structured training in cellular therapy and it will be possible for applicants to develop a research project with a view to undertaking an MD/PhD. There will be an honorary contract with the UCL Cancer Institute for the post-holders.

• Outpatient management of patients receiving CAR-T therapy as well as providing support for patients with complications post-therapy
• Liaising with NCCP and clinical trials team to coordinate work-up and care of patients scheduled for CAR-T and other T-cell therapies therapy
• Liaising with district general hospitals to assist with cellular therapy patients
• Reviewing patients who attend on an emergency basis to the haematology day unit
• Reviewing patients in the weekly T-cell Immunotherapy clinics
• Interaction with lab teams processing translational patient samples and interface with academic trials manufacturing team.
  University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top-quality patient care, excellent education, and world-class research.
  We provide first-class acute and specialist services across eight sites:
  University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)
  National Hospital for Neurology and Neurosurgery
  Royal National ENT and Eastman Dental Hospitals
  University College Hospital Grafton Way Building
  Royal London Hospital for Integrated Medicine
  University College Hospital Macmillan Cancer Centre
  The Hospital for Tropical Diseases
  University College Hospital at Westmoreland Street
  We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women’s health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world class support services including critical care, imaging, nuclear medicine and pathology.
  We are committed to sustainability and have pledged to become a carbon net zero health service, embedding sustainable practice throughout UCLH. We have set an ambitious target of net zero for our direct emissions by 2031 and indirect emissions by 2040.
  For the full Person Specification and more information regarding the main responsibilities of this role, please refer to the attached Job Description.
  Other potential training opportunities
  There are many other training opportunities provided. The trainee will be encouraged, as a member of the Department, to participate in laboratory, clinical, teaching and research activities.
  The duties outlined are not definitive and may be changed according to the needs of the service and training requirements. The post holder may be required to carry out other duties in occasional emergencies and unforeseen circumstances.
  The post is subject to the Terms and Conditions of Service of Hospital Medical and Dental Staff (England & Wales), to the General Whitley Council Conditions of Service and also to the National Health Service Pension Regulations.

The applicant will take a full role in our out of hours on call rota.

• The appointee must hold at least MRCP Part I or equivalent.
• Registration with the General Medical Council is essential.
• Applicants are urged to have at least minimal cover with a medical defence organisation. Come and be a part of the best NHS trust in England to work for, according to our staff*

UCLH top trust to work at in England – for the second year running! : University College London Hospitals NHS Foundation Trust

• In the most recent NHS staff survey UCLH had the highest percentage of staff who said they would recommend us as a place to work, out of all general acute or acute/community NHS trusts in England – for the second year in a row.

UCLH top trust to work at in England – for the second year running! University College London Hospitals NHS Foundation Trust.
Once again, UCLH has received the highest score of all general acute and acute/community NHS trusts in England for staff that would recommend us as a place to work