Downstream Process Scientist

at  Repligen

Overview:
Avitide is a platform technology dedicated to the discovery and development of high-performance affinity chromatography solutions for the biopharmaceutical manufacturing industry. Avitide’s technology platform offers an industry-leading affinity chromatography discovery, development, and supply timeline to reduce the overall costs of biopharmaceutical manufacturing and facilitate the delivery of new medicines to patients. Avitide seeks qualified candidates to build upon their highly motivated and interdisciplinary team and add to the culture of rapid and continuous technology innovation. Avitide is a wholly owned subsidiary of Waltham, MA based Repligen Corporation, a global leader in biopurification.
We are seeking a skilled Downstream Process Scientist to join our dynamic team. The ideal candidate will play a crucial role in testing affinity resins derived from Avitide’s proprietary affinity ligand discovery platform, with emphasis on developing and optimizing downstream processes for the purification of biopharmaceutical products. This position offers an exciting opportunity to contribute to the advancement of novel therapies and medicines that impact global health.
Responsibilities:

The Downstream Process Scientist will be responsible for:

• Rapid development of affinity chromatography purification methods for various biopharmaceuticals, ensuring scalability, and efficiency, with an emphasis on high throughput screening techniques.
• Collaboration: Work collaboratively with cross-functional teams including Ligand Discovery, Analytical Sciences, Resin Manufacturing to ensure project success.
• Troubleshooting: Investigate and resolve technical issues related to affinity resin performance and characterization. A general working knowledge of cutting edge biotherapeutic molecules is a bonus.
• Training and Mentorship: Provide training and mentorship to junior scientists and technicians within the downstream process development team.

Qualifications:

• Education: PhD or Master’s degree in Chemical Engineering, Biochemistry, Biotechnology, or related field.
• Experience: Minimum of 0-3 years (PhD) or 2-5 years (Master’s) of experience in downstream process development within the biopharmaceutical industry.
• Technical Skills: Proficiency in chromatography, filtration, ultrafiltration/diafiltration (UF/DF), and other downstream purification techniques.
• Communication: Excellent verbal and written communication skills, with the ability to effectively present technical information and collaborate across disciplines.
• Problem-Solving: Proven track record in troubleshooting and solving technical challenges related to downstream processes.
• Attributes:
• Detail-oriented with a commitment to data integrity, transparency, and collaborative approaches to problem solving.
• Innovative thinker with a passion for advancing biopharmaceutical technologies.
• Team player who thrives in a collaborative and fast-paced environment.

What Repligen Offers:
Repligen offers you a competitive remuneration package, including a yearly bonus, non-contributory pension, generous PTO, partial compensation on your personal health insurance and flexible working hours. But most importantly Repligen offers you a stimulating, fast-paced environment with steep learning curves and the opportunity to contribute to the healthcare of patients worldwide. All of this with an international team in Waltham, MA

• Rapid development of affinity chromatography purification methods for various biopharmaceuticals, ensuring scalability, and efficiency, with an emphasis on high throughput screening techniques.
• Collaboration: Work collaboratively with cross-functional teams including Ligand Discovery, Analytical Sciences, Resin Manufacturing to ensure project success.
• Troubleshooting: Investigate and resolve technical issues related to affinity resin performance and characterization. A general working knowledge of cutting edge biotherapeutic molecules is a bonus.
• Training and Mentorship: Provide training and mentorship to junior scientists and technicians within the downstream process development team