WORKING WITH US

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .

POSITION SUMMARY

The laboratory-based position will be in the Exploratory Biopharmaceutics (EB) group within the Drug Product Development function. In EB, you will have the ability to impact the lives of patients by working with multi-disciplinary research teams to help in developing novel, efficacious and safe therapeutic molecules. EB is looking for a Scientist with a desire to contribute in the fast-paced early development matrix environment by supporting pre-formulation, physico-chemical characterization, and formulation development of oral and parenteral dosage forms for new small molecule drug candidates in support of preclinical and clinical studies.
The candidate is expected to exhibit a growth mindset and develop expertise in biopharmaceutics and formulation development, represent EB on drug product project teams, execute experiments to deliver knowledge to product development teams.

Key Responsibilities

• Key member of a dynamic scientifically driven team, dedicated to the design, development, and characterization of small molecule drug product formulations.
• Perform physico-chemical characterization and pre-formulation activities to inform early-stage risk assessment and formulation strategy
• Identify, evaluate, and recommend novel drug delivery technologies to develop medicines that provide a better experience for our patients
• Develop oral and parenteral formulations to support clinical and preclinical studies.
• Collaborate with cross-functional team members to develop and optimize formulations and support technology transfer to CMOs and/or other sites for manufacturing and scale up activities.
• Develop experimental protocols and execute in vitro biorelevant dissolution studies for NCEs and drug products.
• Prepare technical reports, batch records, SOPs, manuscripts, and oral presentations as required.
• Support preparation of CMC regulatory documents.
• Support departmental initiatives for assigned projects and methodologies.
• Maintain safety, regulatory, and compliance standards as they relate to the development of pharmaceuticals.

Qualifications & Experience:

• Degree in Pharmaceutical Science, Pharmaceutics, Pharmaceutical Chemistry, Chemical Engineering, or related discipline; Ph.D. with 0-2 years industrial or post-doc experience, M.S. with 2+ years industrial experience or B.S. with 5+ years industrial experience.
• Comprehensive knowledge and understanding of physical pharmacy, fundamentals of pre-formulation, chemistry, stability, and fundamental principles of pharmaceutical science essential for the development of oral and injectable dosage forms.
• Hands on experience with analytical tools including HPLC and dissolution apparatus preferred.
• Hands on experience in formulation development, pharmaceutical processing related to drug product development preferred.
• Experience with designing and developing novel delivery technologies is desired, such as lipid-based drug delivery systems (SMEDDS/SNEDDS), gastro-retentive formulations, particulate systems (nano or micro), hydrogel depots, targeted drug delivery, etc.
• Demonstrated problem-solving and troubleshooting skills.
• Strong verbal and written communication skills.
• Strong interpersonal skills demonstrating effectiveness as a team player on multidisciplinary teams resourced in a flexible and global environment is required.

GPSProdDev

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

• Key member of a dynamic scientifically driven team, dedicated to the design, development, and characterization of small molecule drug product formulations.
• Perform physico-chemical characterization and pre-formulation activities to inform early-stage risk assessment and formulation strategy
• Identify, evaluate, and recommend novel drug delivery technologies to develop medicines that provide a better experience for our patients
• Develop oral and parenteral formulations to support clinical and preclinical studies.
• Collaborate with cross-functional team members to develop and optimize formulations and support technology transfer to CMOs and/or other sites for manufacturing and scale up activities.
• Develop experimental protocols and execute in vitro biorelevant dissolution studies for NCEs and drug products.
• Prepare technical reports, batch records, SOPs, manuscripts, and oral presentations as required.
• Support preparation of CMC regulatory documents.
• Support departmental initiatives for assigned projects and methodologies.
• Maintain safety, regulatory, and compliance standards as they relate to the development of pharmaceuticals