Laboratory Instrumentation Technician

at  Fusion Pharmaceuticals US Inc

Fusion Pharmaceuticals, a member of the AstraZeneca Group, is a clinical-stage oncology company focused on developing next-generation radioconjugates (RCs) as precision medicines. Fusion connects alpha particle emitting isotopes to various targeting molecules to selectively deliver the alpha emitting payloads to tumors. Fusion’s clinical portfolio includes, but is not limited to: FPI-2265 targeting prostate specific membrane antigen (PSMA) for metastatic castration resistant prostate cancer currently in a Phase 2 trial; FPI-1434 targeting insulin-like growth factor 1 receptor currently in a Phase 1 trial; and FPI-2068, a bispecific IgG-based EGFR-cMET targeted radioconjugate currently in a Phase 1 trial. Fusion has multiple other pipeline programs that will soon be entering into early FIH trials. In addition, Fusion is pursuing combination programs between RCs and other therapeutic modalities including DNA Damage Response Inhibitors (DDRis) and immune-oncology agents. To support execution for these programs, Fusion has a fully operational Good Manufacturing Practice (GMP) compliant state-of-the-art radioconjugate manufacturing facility to meet supply demand for our growing pipeline of RCs.
The Laboratory Instrumentation Technician will be reporting to the Laboratory Manager and will be a part of a pre-clinical research team that is responsible for the discovery, production, development, validation, and advancement of the next generation of radiotherapeutics and nuclear imaging probes. This position will support a broad range of preclinical development activities, focusing on the maintenance and upkeep of all laboratory equipment and instrumentation. This position is full-time, in-person, and located in Hamilton, Ontario, Canada.

Responsibilities:

• Establish and maintain inventories of all lab equipment/instruments along with all required maintenance and cleaning schedules
• Perform all in-house maintenance and upkeep
• Organize equipment maintenance and certification with outside service providers in accordance with pre-planned agenda (for example: Biosafety cabinets, incubators, freezers and other general lab equipment)
• Maintain external relationships with key service providers
• Oversee service technicians during on-site visits for scheduled maintenance and repairs
• Organize and receive equipment deliveries
• Continuously monitor equipment and instrumentation for optimal performance and report to the Laboratory Manager any required actions needed
• Assist in investigating new laboratory instrumentation/equipment and make appropriate recommendations to the Laboratory Manager
• Assist in the day-to-day operations of the Fusion laboratories, or any other assigned tasks as needed

Qualifications:

• Bachelor’s degree in Science, Health Sciences, Animal Sciences, Biology, Biochemistry, or a related field
• 2-5 years of experience working in research or clinical lab environments
• Experience with basic maintenance of analytical and preparative HPLCs, LC-MS systems, pH meters, analytical balances and lyophilizers
• Experience with flow cytometry, microscopes, cryostat, embedding and histology equipment
• Highly organized with proven ability to work independently and proactively
• Excel working in a collaborative environment as a member of a multidisciplinary team
• Willingness to take on new tasks and responsibilities as required
• Experience with the safe handling of radioactive and biohazardous materials/waste is an asset
• Knowledge of good laboratory practices is an asset
• Proficiency with spreadsheets (e.g., Excel, Google Sheets) and word processing software (e.g., Word)

Fusion Pharmaceuticals is an equal opportunity employer that is committed to inclusive, barrier-free recruitment and selection processes, if contacted for an interview, please advise Human Resources if you Require accommodation.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

• Establish and maintain inventories of all lab equipment/instruments along with all required maintenance and cleaning schedules
• Perform all in-house maintenance and upkeep
• Organize equipment maintenance and certification with outside service providers in accordance with pre-planned agenda (for example: Biosafety cabinets, incubators, freezers and other general lab equipment)
• Maintain external relationships with key service providers
• Oversee service technicians during on-site visits for scheduled maintenance and repairs
• Organize and receive equipment deliveries
• Continuously monitor equipment and instrumentation for optimal performance and report to the Laboratory Manager any required actions needed
• Assist in investigating new laboratory instrumentation/equipment and make appropriate recommendations to the Laboratory Manager
• Assist in the day-to-day operations of the Fusion laboratories, or any other assigned tasks as neede