Lead Researcher or Senior Researcher - Tumor Cell Biology (Martine Roussel Lab)

at  St Jude Childrens Research Hospital

The Lead or Senior Researcher will play a pivotal role in the Martine Roussel Lab, conducting research focused on identifying and validating novel vulnerabilities in pediatric brain tumors. The candidate will utilize CRISPR-Cas screening techniques to explore therapeutic targets for medulloblastoma ETMR and ATRT.
Check out Martine Roussel, her lab, and the Department of Tumor Cell Biology to learn more about their groundbreaking research and the team!

MINIMUM EDUCATION AND/OR TRAINING:

• Bachelor’s degree in a relevant scientific area is required

LEAD RESEARCHER MINIMUM EXPERIENCE:

• Five (5) years of relevant, post-degree work experience is required
• Two (2) years of relevant post-degree work experience is required with a Master’s degree
• No experience is required with a PHD
  Salary range: $65,520.00/yr. - $114,400.00/yr.

SENIOR RESEARCHER MINIMUM EXPERIENCE:

• Two (2) years of relevant, post-degree work experience is required.
• No experience is required with a Master’s degree.
  Salary range: $60,320.00/yr. - $105,040.00/yr.

• Perform CRISPR-Cas screens to identify potential vulnerabilities in pediatric brain tumors.
• Culture neuronal tumor cells and conduct orthotopic implants in murine models.
• Harvest tumors, extract RNA and DNA, and conduct molecular analysis (e.g., RNA-sequencing).
• Contribute to the Pediatric Dependency Accelerator Project between St. Jude Children’s Hospital and the Broad Institute.
• Work independently within broad guidelines and subject to periodic review.
• Performs laboratory experiments using existing, modified or newly developed techniques/protocols
• Sets up protocols, trouble shoots experiments using new or modified laboratory techniques
• Identifies experimental data pertinent to the analysis problem. Processes, organizes and summarizes data and reports results
• May assist in the drafting and editing of manuscripts.
• Provides basic lab operation support to include equipment maintenance and purchasing. Monitors inventory and orders lab supplies as needed. Performs calibration of instruments and equipment as necessary.
• Provides guidance to entry-level employees.
• Performs other related duties as assigned in order to meet the goals of the department and institution
• Maintains regular and predictable attendance