MRC Postdoctoral Research Scientist LMS 2485

at  Medical Research Council

Open Date
17/09/2024, 09:30
Close Date
01/10/2024, 23:55
Research Institute
MRC Laboratory of Medical Sciences
As this job does not fulfil the UK Government minimum salary criterion for obtaining sponsored migrant worker status we will be unable to apply for sponsorship for anyone not eligible to work in the UK. At interview, all shortlisted candidates are required to bring with them identification documents and original documents that prove they hold or can obtain the right to work in the UK. You can check your eligibility here: https://www.gov.uk/check-uk-visa/y
Research Institute / Unit Information
The LMS is a world-class research laboratory where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. Funded by the MRC as part of UK Research and Innovation, the LMS has a collaborative working culture and new state-of-the-art building based in the heart of West London in the Hammersmith Hospital Campus (W12).
The LMS aims to deliver transdisciplinary team science, in synergistic interaction with Imperial College and the wider national research environment. Part of achieving this, is to recruit new talent and support postdoctoral scientists to become world leaders in their area of science.
UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org
Band

MRC - 4

Location
London
Salary
Salary: £39,375 plus London allowances (£3,913 & £1,472) per annum
Allowances
Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two and £1,800 in the third year.
Contract Type
Fixed Term
Job Type
Science
Full Time / Part Time
Full Time
Contract Length
28 months
Job Description

EDUCATION / QUALIFICATIONS / TRAINING REQUIRED (WILL BE ASSESSED FROM APPLICATION FORM):

Essential:

• PhD (or equivalent) in a related area of research

Previous work experience required (will be assessed from application form and at interview):

Essential:

• Experience of working with primary human endothelial cells (HUVECs);
• Experience of proteomic and transcriptomic data analysis
• Experience of mouse breeding and metabolic phenotyping (current holder of PIL essential)

Desirable:

• Expertise in AMPK signalling, and in particular its role in hypoxia would be a substantial advantage

Knowledge and experience (will be assessed from application form and at interview):

Essential:

• Ability to develop and apply new concepts
• Expertise in in vivo metabolic phenotyping in mice
• Experience of histological methods, particularly liver and endothelial cells
• Creative approach to problem solving
• Good written communication skills in English

Personal skills / Behaviours / Qualities (will be assessed at the interview):

Essential:

• Ability to work independently and as part of a team
• Good verbal communication skills in English
• Ability to constructively engage in scientific discussions
• Critical evaluation of data

Further Information
Please also indicate in the cover letter when you would be able to take up the position. Please quote reference number LMS 2485.
The MRC is a unique working environment where scientific researchers and professional support staff can actively partake in world class innovation and collaboration opportunities and their skills and knowledge through accessing a wide catalogue of training & development, including professional registration with the Science Council.
In addition, MRC (part of UKRI) provides its community of employees access to a whole host of useful benefits, including a defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme. Please follow this link to find out more - Benefits
Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We warmly invite people from diverse backgrounds and heritage, including people who identify as having a disability, to apply for a role that excites them. As “Disability Confident” employers, we guarantee to interview all applicants who have disclosed they have a disability and who meet the minimum criteria for the vacancy.
UKRI supports research in areas that include animal health, agriculture and food security, and bioscience for health which includes research on animals, genetic modification and stem cell research. Whilst you may not have direct involvement in this type of research, you should consider whether this conflicts with your personal values or beliefs.
We will conduct a full and comprehensive pre-employment check as an essential part of the recruitment process on all individuals that are offered a position with UKRI. This will include a security check and an extreme organisations affiliation check. The role holder will be required to have the appropriate level of security screening/vetting required for the role. UKRI reserves the right to run or re-run security clearance as required during the course of employment

OVERALL PURPOSE

This project will explore the role of AMPK in endothelial cells.

MAIN RESPONSIBILITIES:

• To plan and carry out research
• To write and publish the results
• To form good working relationships with other members of the group
• To assist others and co-supervise students when required
• To contribute to the development and maintenance of the group’s experimental or computational infrastructure as appropriate
  Person Specification